Literature DB >> 2310661

Comparative haemodynamic effects of intravenous nisoldipine and hydralazine in congestive heart failure.

B Haitas1, T E Meyer, M E Angel, E Reef.   

Abstract

The acute haemodynamic effects of intravenous nisoldipine and hydralazine were compared in nine patients with heart failure. Both agents caused qualitatively similar effects, reducing both left ventricular preload and afterload, with reductions in systemic vascular resistance and increases in cardiac output. However, the effect of hydralazine was significantly greater and of longer duration than nisoldipine, and was associated with side effects in four patients. This, and previously reported data, suggests that nisoldipine may be useful in patients with ischaemia and concomitant heart failure.

Entities:  

Mesh：

Substances：

Year:  1990        PMID： 2310661      PMCID： PMC1380140          DOI： 10.1111/j.1365-2125.1990.tb03650.x

Source DB:  PubMed          Journal:  Br J Clin Pharmacol        ISSN： 0306-5251            Impact factor:   4.335


  7 in total

1.  [Study of the effects on coronary circulation and myocardial metabolism of a single intravenous dose of dihydralazine in 10 cases of primary myocardiopathy].

Authors:  F Fernandez; W Sprogis; M Baclet; C Lelguen; A Gerbaux
Journal:  Arch Mal Coeur Vaiss       Date:  1980-04

2.  Acute inotropic effects of intravenous nifedipine and its vehicle compared with saline: a double-blind study of systolic time intervals in normal subjects.

Authors:  T J Walley; A M Heagerty; K L Woods; R F Bing; J E Pohl; D B Barnett
Journal:  Br J Clin Pharmacol       Date:  1988-02       Impact factor: 4.335

3.  Effect of the second-generation calcium channel blocker nisoldipine on left ventricular contractility in cardiac failure.

Authors:  B S Lewis; A Shefer; A Merdler; M Y Flugelman; R Hardoff; D A Halon
Journal:  Am Heart J       Date:  1988-06       Impact factor: 4.749

4.  Comparison of the acute hemodynamic response to intravenous nisoldipine (Bay k 5552) and intravenous nifedipine for left ventricular dysfunction secondary to myocardial infarction.

Authors:  C A Nienaber; R P Spielmann; W Aschenberg; A Fehr; A Clausen; W Bleifeld
Journal:  Am J Cardiol       Date:  1987-10-01       Impact factor: 2.778

5.  Determinants of circulatory response to intravenous hydralazine in congestive heart failure.

Authors:  J R Wilson; M St John Sutton; J S Schwartz; N Ferraro; N Reichek
Journal:  Am J Cardiol       Date:  1983-08       Impact factor: 2.778

6.  Coronary and systemic hemodynamic effects of intravenous nisoldipine.

Authors:  A L Soward; P J De Feyter; P G Hugenholtz; P W Serruys
Journal:  Am J Cardiol       Date:  1986-12-01       Impact factor: 2.778

7.  Arterial vasodilator, systemic and coronary hemodynamic effects of nisoldipine in congestive heart failure secondary to ischemic or dilated cardiomyopathy.

Authors:  W Kiowski; P Erne; M Pfisterer; J Mueller; F R Buehler; F Burkart
Journal:  Am J Cardiol       Date:  1987-05-01       Impact factor: 2.778
  7 in total
  1 in total

1.  Acute effects of intravenous nisoldipine on left ventricular function after acute myocardial infarction.

Authors:  E E van der Wall; V M Cats; J C Chin; E J Pauwels; A V Bruschke
Journal:  Cardiovasc Drugs Ther       Date:  1994-05       Impact factor: 3.727
  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.