Literature DB >> 231063

Influence of magnesium on the secretion and action of parathyroid hormone.

K S Nair, I M Holdaway, M C Evans, A D Cameron.   

Abstract

The interactions of serum levels of magnesium and parathyroid hormone (PTH) have been studied in a patient with hypomagnesemia and hypocalcemia following intestinal bypass surgery for obesity. When serum magnesium was low serum PTH was not stimulated by hypocalcemia. With correction of magnesium deficiency hypocalcemia was associated with elevation of serum PTH levels. Infusion of exogenous PTH induced a clearly detectable renal response in the presence of hypomagnesemia but the response was diminished when serum magnesium was elevated. In this patient it appears that hypomagnesemia suppressed parathyroid gland activity, leaving the renal action of PTH intact.

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Year:  1979        PMID： 231063     DOI： 10.1007/BF03350414

Source DB:  PubMed          Journal:  J Endocrinol Invest        ISSN： 0391-4097            Impact factor:   4.256


  22 in total

1.  Immunoassay of thyrocalcitonin. I. The method and its serological specificity.

Authors:  A H Tashjian
Journal:  Endocrinology       Date:  1969-01       Impact factor: 4.736

2.  Immunoradiometric assay of parathyroid hormone.

Authors:  G M Addison; C N Hales; J S Woodhead; J L O'Riordan
Journal:  J Endocrinol       Date:  1971-03       Impact factor: 4.286

3.  A modified index of phosphate excretion.

Authors:  B E Nordin; L Bulusu
Journal:  Postgrad Med J       Date:  1968-01       Impact factor: 2.401

4.  The influence of plasma magnesium concentration on parathyroid hormone secretion.

Authors:  R M Buckle; A D Care; C W Cooper; H J Gitelman
Journal:  J Endocrinol       Date:  1968-12       Impact factor: 4.286

5.  Hypocalcemia due to hypomagnesemia and reversible parathyroid hormone unresponsiveness.

Authors:  H Estep; W A Shaw; C Watlington; R Hobe; W Holland; S G Tucker
Journal:  J Clin Endocrinol Metab       Date:  1969-06       Impact factor: 5.958

6.  Pathogenesis of hypocalcemia in primary hypomagnesemia: normal end-organ responsiveness to parathyroid hormone, impaired parathyroid gland function.

Authors:  S M Suh; A H Tashjian; N Matsuo; D K Parkinson; D Fraser
Journal:  J Clin Invest       Date:  1973-01       Impact factor: 14.808

7.  Studies on mechanisms of hypocalcemia of magnesium depletion.

Authors:  C R Reddy; J W Coburn; D L Hartenbower; R M Friedler; A S Brickman; S G Massry; J Jowsey
Journal:  J Clin Invest       Date:  1973-12       Impact factor: 14.808

8.  Assay of plasma 25-hydroxy vitamin D.

Authors:  J F Morris; M Peacock
Journal:  Clin Chim Acta       Date:  1976-11-01       Impact factor: 3.786

9.  Evidence for suppression of parathyroid gland activity by hypermagnesemia.

Authors:  S G Massry; J W Coburn; C R Kleeman
Journal:  J Clin Invest       Date:  1970-09       Impact factor: 14.808

10.  Evidence for parathyroid failure in magnesium deficiency.

Authors:  C S Anast; J M Mohs; S L Kaplan; T W Burns
Journal:  Science       Date:  1972-08-18       Impact factor: 47.728
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  3 in total

Review 1.  Hypoparathyroidism.

Authors:  John P Bilezikian
Journal:  J Clin Endocrinol Metab       Date:  2020-06-01       Impact factor: 5.958

2.  [Hypomagnesemia-induced hypocalcemia: functional hypoparathyroidism, parathyroid hormone- and vitamin D-resistant].

Authors:  E Leicht; G Biro; E Keck; H J Langer
Journal:  Klin Wochenschr       Date:  1990-07-05

3.  Assessing the Patient Experience of Hypoparathyroidism Symptoms: Development of the Hypoparathyroidism Patient Experience Scale-Symptom (HPES-Symptom).

Authors:  Meryl Brod; Laura Tesler Waldman; Alden Smith; David Karpf
Journal:  Patient       Date:  2020-04       Impact factor: 3.883
  3 in total

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