Literature DB >> 23105556

Urinary catecholamine metabolites: Capillary gas chromatography method and experience with 12 cases of neuroblastoma.

Sanja Grkovic1, Rajko Nikolic, Maja Dordevic, Ljubomir Stojanov.   

Abstract

We propose a rapid, simple metodology for routine analysis of human urine to detect vanillylmandelic and homovanillic acid related to neuroblastoma. The assay were specific capillary gas chromatography with flame ionization detection. In this methodology an internal standard is used and the procedure involves ethyl ester formation without isolation of the compounds of interest. The run time is 36 minutes. We also report quantitative results for urinary vanillylmandelic and homovanillic acid in neuroblastoma patients, demonstrating the diagnostic value of this method.

Entities:  

Keywords:  Capillary gas chromatography; Homovanillic acid; diagnostic aids; neuroblastoma; vanillylmandelic acid

Year:  2005        PMID： 23105556      PMCID： PMC3453848          DOI： 10.1007/BF02867423

Source DB:  PubMed          Journal:  Indian J Clin Biochem        ISSN： 0970-1915


  9 in total

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Journal:  JAMA       Date:  1963-03-09       Impact factor: 56.272

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Authors:  C Weinkove
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Journal:  Cancer Causes Control       Date:  1997-09       Impact factor: 2.506

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Authors:  P Husek
Journal:  Clin Chem       Date:  1997-10       Impact factor: 8.327

5.  Method of measurement of urinary homovanillic acid and vanillylmandelic acid by gas chromatography-mass spectrometry suitable for neuroblastoma screening.

Authors:  J A Seviour; A C McGill; G Dale; A W Craft
Journal:  J Chromatogr       Date:  1988-11-18

6.  Incidence of cancer in children in the United States. Sex-, race-, and 1-year age-specific rates by histologic type.

Authors:  J G Gurney; R K Severson; S Davis; L L Robison
Journal:  Cancer       Date:  1995-04-15       Impact factor: 6.860

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Authors:  C A Stiller; D M Parkin
Journal:  Int J Cancer       Date:  1992-10-21       Impact factor: 7.396

Review 8.  Measurement of catecholamines and their metabolites.

Authors:  Robert T Peaston; Cyril Weinkove
Journal:  Ann Clin Biochem       Date:  2004-01       Impact factor: 2.057

9.  Capillary gas-chromatographic determination of urinary homovanillic acid and vanillylmandelic acid.

Authors:  M Tuchman; P J Crippin; W Krivit
Journal:  Clin Chem       Date:  1983-05       Impact factor: 8.327
  9 in total

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