Literature DB >> 2310548

The effect of taurine supplementation on the ototoxicity of neomycin in guinea pigs.

I S Kay1, W E Davies.   

Abstract

Experiments have been performed to examine the effects of taurine supplementation on the ototoxicity of neomycin. It was found that concurrent administration of taurine and neomycin produced a greater degree of ototoxicity, as evidenced by increases in hearing thresholds, than with neomycin alone. The results are discussed in light of a recently proposed mechanism of aminoglycoside ototoxicity.

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Year:  1990        PMID: 2310548     DOI: 10.1007/bf00240947

Source DB:  PubMed          Journal:  Eur Arch Otorhinolaryngol        ISSN: 0937-4477            Impact factor:   2.503


  8 in total

1.  Progressive ototoxicity of neomycin monitored using derived brainstem response audiometry.

Authors:  R K Shepherd; G M Clark
Journal:  Hear Res       Date:  1985-05       Impact factor: 3.208

2.  Effect of taurine on 45Ca2+ accumulation in rat brain synaptosomes.

Authors:  H Pasantes-Morales; A Gamboa
Journal:  J Neurochem       Date:  1980-01       Impact factor: 5.372

3.  Effects of taurine on calcium ion uptake and protein phosphorylation in rat retinal membrane preparations.

Authors:  J B Lombardini
Journal:  J Neurochem       Date:  1985-07       Impact factor: 5.372

4.  Effect of taurine on calcium accumulation in resting and depolarised insect synaptosomes.

Authors:  P S Whitton; R A Nicholson; R H Strang
Journal:  J Neurochem       Date:  1988-06       Impact factor: 5.372

5.  Three molecular steps of aminoglycoside ototoxicity demonstrated in outer hair cells.

Authors:  S E Williams; H P Zenner; J Schacht
Journal:  Hear Res       Date:  1987       Impact factor: 3.208

Review 6.  Inositol trisphosphate, a novel second messenger in cellular signal transduction.

Authors:  M J Berridge; R F Irvine
Journal:  Nature       Date:  1984 Nov 22-28       Impact factor: 49.962

Review 7.  Aminoglycoside toxicity - a review of clinical studies published between 1975 and 1982.

Authors:  G Kahlmeter; J I Dahlager
Journal:  J Antimicrob Chemother       Date:  1984-01       Impact factor: 5.790

8.  Evidence that phosphoinositides mediate motility in cochlear outer hair cells.

Authors:  J Schacht; H P Zenner
Journal:  Hear Res       Date:  1987-12       Impact factor: 3.208

  8 in total
  1 in total

Review 1.  Effect of taurine supplementation on growth and development in preterm or low birth weight infants.

Authors:  A Verner; S Craig; W McGuire
Journal:  Cochrane Database Syst Rev       Date:  2007-10-17
  1 in total

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