1, 25-Dihydroxycholecalciferol (1,25-(OH)(2) D(3)) levels in osteoporosis.

In the present study primary involution osteoporosis and vitamin D levels were studied in 60 subjects including thirty controls. The biochemical analysis of serum calcium, phosphorus, ALP, albumin and vitamin D(3) (1,25-(OH)(2) D(3)) levels were significantly decreased in osteoporotic patients when compared to non-osteoporotic control group. There was a significant correlation of magnitude of sun exposure with 1,25-(OH)(2) D(3) levels. Similarly, vitamin D intake in the diet has a significant correlation with 1,25-(OH)(2) D(3) concentration. However, no correlation could be obtained between vitamin D(3) levels with increasing age. Among the biochemical markers serum calcium, phosphorus, ALP and albumin could not be correlated with 1,25-(OH)(2) D(3) levels.