Literature DB >> 23105449

Stability of total and free prostate specific antigen in serum samples at different storage conditions.

G Rajani Kumari1, T Malati.   

Abstract

The present preliminary study was performed to find out stability of total prostate specific antigen (PSA) and free prostate specific antigen (FPSA) in serum of healthy males as well as in patients of benign and malignant disorders of prostate at various freezing and nonfreezing temperatures and at different duration of time.The results of our study indicated long-term stability of both the analytes in frozen serum. Serum total and free PSA were stable only for three to four days in regular refrigerators in unfrozen states. Clotted blood kept at room temperature (25°C-30°C) did not cause change in concentrations of both the analytes for twenty four hours.

Entities:  

Keywords:  BPH; Cancer Prostate; Free PSA and Total PSA

Year:  2004        PMID： 23105449      PMCID： PMC3454192          DOI： 10.1007/BF02894250

Source DB:  PubMed          Journal:  Indian J Clin Biochem        ISSN： 0970-1915


  6 in total

1.  Storage conditions for serum for estimating prostate-specific antigen.

Authors:  B Simm; M Gleeson
Journal:  Clin Chem       Date:  1991-01       Impact factor: 8.327

2.  Preanalytical determinants of total and free prostate-specific antigen and their ratio: blood collection and storage conditions.

Authors:  K Jung; P von Klinggräff; B Brux; P Sinha; D Schnorr; S A Loening
Journal:  Clin Chem       Date:  1998-03       Impact factor: 8.327

3.  In vitro stability of free prostate-specific antigen (PSA) and prostate-specific antigen (PSA) complexed to alpha 1-antichymotrypsin in blood samples.

Authors:  T Piironen; K Pettersson; M Suonpää; U H Stenman; J E Oesterling; T Lövgren; H Lilja
Journal:  Urology       Date:  1996-12       Impact factor: 2.649

4.  Double-label time-resolved immunofluorometric assay of prostate-specific antigen and of its complex with alpha 1-antichymotrypsin.

Authors:  J Leinonen; T Lövgren; T Vornanen; U H Stenman
Journal:  Clin Chem       Date:  1993-10       Impact factor: 8.327

5.  Free and complexed prostate-specific antigen (PSA): in vitro stability, epitope map, and development of immunofluorometric assays for specific and sensitive detection of free PSA and PSA-alpha 1-antichymotrypsin complex.

Authors:  K Pettersson; T Piironen; M Seppälä; L Liukkonen; A Christensson; M T Matikainen; M Suonpää; T Lövgren; H Lilja
Journal:  Clin Chem       Date:  1995-10       Impact factor: 8.327

6.  Serum concentrations of prostate specific antigen and its complex with alpha 1-antichymotrypsin before diagnosis of prostate cancer.

Authors:  U H Stenman; M Hakama; P Knekt; A Aromaa; L Teppo; J Leinonen
Journal:  Lancet       Date:  1994-12-10       Impact factor: 79.321
  6 in total
  3 in total

1.  Enhanced detection sensitivity of prostate-specific antigen via PSA-conjugated gold nanoparticles based on localized surface plasmon resonance: GNP-coated anti-PSA/LSPR as a novel approach for the identification of prostate anomalies.

Authors:  M H Jazayeri; H Amani; A A Pourfatollah; A Avan; G A Ferns; H Pazoki-Toroudi
Journal:  Cancer Gene Ther       Date:  2016-10-14       Impact factor: 5.987

2.  Prostate specific antigen in patients of benign prostate hypertrophy and carcinoma prostate.

Authors:  T Malati; G Rajani Kumari; P V L N Murthy; Ch Ram Reddy; B Surya Prakash
Journal:  Indian J Clin Biochem       Date:  2006-03

3.  Tumour markers: An overview.

Authors:  T Malati
Journal:  Indian J Clin Biochem       Date:  2007-09
  3 in total

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