Literature DB >> 23105366

Antioxidant effect ofPhyllanthus emblica fruits on healing of indomethacin induced gastric ulcer in rats.

Anita Pakrashi1, Srikanta Pandit, Sandip K Bandyopadhyay, Satyesh C Pakrashi.   

Abstract

Post-treatment of the indomethacin induced ulcerated rats at the optimal dose of 100 mg/kg body-wt. orally for 7 consecutive days with the lyophilized aqueous extract of the fruits ofPhyllanthus emblica L. syn.Emblica officinalis Gaertn. (Euphorbiaceae) exhibited highly significant (p<0.001) enhancement of secretion of catalase, reduced glutathione and decrease in malonyldialdehyde (MDA). Furthermore, the gross morphological observation and highly significant (p<0.001) decrease of ulcer index (81.43%) indicated healing effect of the extract on gastric ulcer.

Entities:  

Keywords:  Antioxidant; Phyllanthus emblica; antiulcer; healing

Year:  2003        PMID： 23105366      PMCID： PMC3453744          DOI： 10.1007/BF02867660

Source DB:  PubMed          Journal:  Indian J Clin Biochem        ISSN： 0970-1915


  14 in total

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Authors:  M Ligumsky; M Sestieri; E Okon; I Ginsburg
Journal:  Scand J Gastroenterol       Date:  1995-09       Impact factor: 2.423

10.  Potent antiulcerogenic activity of ethanol extract of leaf ofPiper betle Linn by antioxidative mechanism.

Authors:  Biswajit Majumdar; Susri Ray Chaudhuri; Arun Ray; Sandip K Bandyopadhyay
Journal:  Indian J Clin Biochem       Date:  2002-01
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  3 in total

Review 1.  Efficacy and safety of herbal medicines in treating gastric ulcer: a review.

Authors:  Wei-Ping Bi; Hui-Bin Man; Mao-Qiang Man
Journal:  World J Gastroenterol       Date:  2014-12-07       Impact factor: 5.742

2.  Gastroprotective effects of arctigenin of Arctium lappa L. on a rat model of gastric ulcers.

Authors:  Xiao-Mei Li; Yu Miao; Qin-Yong Su; Jing-Chun Yao; Hong-Hua Li; Gui-Min Zhang
Journal:  Biomed Rep       Date:  2016-10-04

3.  Evaluation of Cellular Antioxidant and Antiproliferative Activities of Five Main Phyllanthus Emblica L. Cultivars in China.

Authors:  Y Li; H Y Sun; X Y Yu; D Liu; H X Wan
Journal:  Indian J Pharm Sci       Date:  2015 May-Jun       Impact factor: 0.975
  3 in total

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