Literature DB >> 23105342

Apolipoprotein E4 polymorphism as risk factor for coronary heart disease among Indian subjects.

Tester F Ashavaid1, Seema P Todur, Kappiareth G Nair.   

Abstract

Apolipoprotein E genotypes and lipid and lipoprotein levels were determined in hypercholesterolemic and angiographically vertified CHD subjects and compared against 90 normolipidemic controls. The ε4 allele was significantly prevalent in the hypercholesterolemic and CHD subjects. Significant increase in total cholesterol levels in apo ε4 containing subjects were observed in the hypercholesterolemic and CHD group. The study suggests that the ε4 allele by influencing the lipid levels could act as a risk factor for CHD.

Entities:  

Keywords:  Apolipoprotein E genotypes; alleles

Year:  2002        PMID： 23105342      PMCID： PMC3453726          DOI： 10.1007/BF02867947

Source DB:  PubMed          Journal:  Indian J Clin Biochem        ISSN： 0970-1915


  28 in total

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Journal:  Clin Chem Lab Med       Date:  1998-08       Impact factor: 3.694

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Journal:  Eur J Clin Invest       Date:  1998-04       Impact factor: 4.686

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Journal:  Indian Heart J       Date:  1995 Jul-Aug
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  2 in total

1.  Association of CETP and LIPC Gene Polymorphisms with HDL and LDL Sub-fraction Levels in a Group of Indian Subjects: A Cross-Sectional Study.

Authors:  Seema P Todur; Tester F Ashavaid
Journal:  Indian J Clin Biochem       Date:  2012-09-27

2.  Genetic analysis of Indian subjects with clinical features of possible type IIa hypercholesterolemia.

Authors:  Altaf A Kondkar; Kappiareth G Nair; Tester F Ashavaid
Journal:  J Clin Lab Anal       Date:  2007       Impact factor: 2.352
  2 in total

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