| Literature DB >> 2310523 |
Abstract
Molecular modeling is used to study the opening pathways of bases within a B-DNA oligomer. It is demonstrated that many open states are possible for a single base pair, although a preference for opening towards the major groove of the double helix is found. In addition we show that opening is strongly influenced by the nature of the base involved and is also coupled in many cases to DNA bending.Mesh：
Substances：
Year: 1990 PMID： 2310523 DOI： 10.1080/07391102.1990.10508532
Source DB: PubMed Journal: J Biomol Struct Dyn ISSN： 0739-1102