Literature DB >> 23102815

Control of multi-drug-resistant Acinetobacter baumannii outbreaks in an intensive care unit: feasibility and economic impact of rapid unit closure.

S Ayraud-Thévenot1, C Huart, O Mimoz, M Taouqi, C Laland, A Bousseau, O Castel.   

Abstract

From January to May 2006, a nosocomial outbreak caused by a multi-drug-resistant strain of Acinetobacter baumannii (MDRAB) occurred in a multi-specialty surgical ICU (SICU). During this episode, 20 patients were colonized by an identical MDRAB strain. Despite introduction of control measures, the outbreak was only stopped after complete closure of the unit. When a second MDRAB outbreak was confirmed in the same unit in January 2009, the SICU was closed as soon as possible. This measure allowed faster control of the outbreak, which only involved seven patients and lasted for 25 days. The economic impact of the outbreak was also considerably lower; estimated costs were €202,214 in 2009 compared with €539,325 in 2006. This study found that rapid closure of the SICU, with patients cohorted elsewhere, was a cost-effective way of controlling an MDRAB outbreak.
Copyright © 2012 The Healthcare Infection Society. Published by Elsevier Ltd. All rights reserved.

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Year:  2012        PMID: 23102815     DOI: 10.1016/j.jhin.2012.08.016

Source DB:  PubMed          Journal:  J Hosp Infect        ISSN: 0195-6701            Impact factor:   3.926


  15 in total

1.  Task force on management and prevention of Acinetobacter baumannii infections in the ICU.

Authors:  José Garnacho-Montero; George Dimopoulos; Garyphallia Poulakou; Murat Akova; José Miguel Cisneros; Jan De Waele; Nicola Petrosillo; Harald Seifert; Jean François Timsit; Jordi Vila; Jean-Ralph Zahar; Matteo Bassetti
Journal:  Intensive Care Med       Date:  2015-10-05       Impact factor: 17.440

2.  Colistin and Fusidic Acid, a Novel Potent Synergistic Combination for Treatment of Multidrug-Resistant Acinetobacter baumannii Infections.

Authors:  Lynette M Phee; Jonathan W Betts; Binutha Bharathan; David W Wareham
Journal:  Antimicrob Agents Chemother       Date:  2015-05-18       Impact factor: 5.191

3.  Protective Effect of a Synbiotic against Multidrug-Resistant Acinetobacter baumannii in a Murine Infection Model.

Authors:  Takashi Asahara; Akira Takahashi; Norikatsu Yuki; Rumi Kaji; Takuya Takahashi; Koji Nomoto
Journal:  Antimicrob Agents Chemother       Date:  2016-04-22       Impact factor: 5.191

Review 4.  Code blue: Acinetobacter baumannii, a nosocomial pathogen with a role in the oral cavity.

Authors:  A M Richards; Y Abu Kwaik; R J Lamont
Journal:  Mol Oral Microbiol       Date:  2014-09-27       Impact factor: 3.563

5.  Prevalence of Device-associated Nosocomial Infections Caused By Gram-negative Bacteria in a Trauma Intensive Care Unit in Libya.

Authors:  Abdulaziz Zorgani; Atef Abofayed; Abdulhakim Glia; Ashrf Albarbar; Sami Hanish
Journal:  Oman Med J       Date:  2015-07

6.  A longitudinal assessment of antimicrobial susceptibility among important pathogens collected as part of the Tigecycline Evaluation and Surveillance Trial (T.E.S.T.) in France between 2004 and 2012.

Authors:  Vincent Cattoir; Michael J Dowzicky
Journal:  Antimicrob Resist Infect Control       Date:  2014-12-01       Impact factor: 4.887

7.  Emergence of carbapenem-resistant Acinetobacter baumannii as the major cause of ventilator-associated pneumonia in intensive care unit patients at an infectious disease hospital in southern Vietnam.

Authors:  Nguyen Thi Khanh Nhu; Nguyen Phu Huong Lan; James I Campbell; Christopher M Parry; Corinne Thompson; Ha Thanh Tuyen; Nguyen Van Minh Hoang; Pham Thi Thanh Tam; Vien Minh Le; Tran Vu Thieu Nga; Tran Do Hoang Nhu; Pham Van Minh; Nguyen Thi Thu Nga; Cao Thu Thuy; Le Thi Dung; Nguyen Thi Thu Yen; Nguyen Van Hao; Huynh Thi Loan; Lam Minh Yen; Ho Dang Trung Nghia; Tran Tinh Hien; Louise Thwaites; Guy Thwaites; Nguyen Van Vinh Chau; Stephen Baker
Journal:  J Med Microbiol       Date:  2014-07-18       Impact factor: 2.472

8.  Biofilm Formation and Motility Depend on the Nature of the Acinetobacter baumannii Clinical Isolates.

Authors:  Saranya Vijayakumar; Sangeetha Rajenderan; Shakti Laishram; Shalini Anandan; Veeraraghavan Balaji; Indranil Biswas
Journal:  Front Public Health       Date:  2016-05-24

Review 9.  Use of ward closure to control outbreaks among hospitalized patients in acute care settings: a systematic review.

Authors:  Holly Wong; Katherine Eso; Ada Ip; Jessica Jones; Yoojin Kwon; Susan Powelson; Jill de Grood; Rose Geransar; Maria Santana; A Mark Joffe; Geoffrey Taylor; Bayan Missaghi; Craig Pearce; William A Ghali; John Conly
Journal:  Syst Rev       Date:  2015-11-07

10.  Costs associated with implementation of a strict policy for controlling spread of highly resistant microorganisms in France.

Authors:  Gabriel Birgand; Christophe Leroy; Simone Nerome; Liem Binh Luong Nguyen; Isabelle Lolom; Laurence Armand-Lefevre; Céline Ciotti; Bertrand Lecorre; Géraldine Marcade; Vincent Fihman; Marie-Hélène Nicolas-Chanoine; Camille Pelat; Anne Perozziello; Bruno Fantin; Yazdan Yazdanpanah; Jean-Damien Ricard; Jean-Christophe Lucet
Journal:  BMJ Open       Date:  2016-01-29       Impact factor: 2.692

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