Literature DB >> 23101976

Alcohol metabolism.

Arthur I Cederbaum1.   

Abstract

This article describes the pathways and factors that modulate blood alcohol levels and metabolism and describes how the body disposes of alcohol. The various factors that play a role in the distribution of alcohol in the body, influence the absorption of alcohol, and contribute to first-pass metabolism of alcohol are described. Most alcohol is oxidized in the liver, and general principles and overall mechanisms for alcohol oxidation are summarized. The kinetics of alcohol elimination in-vivo and the various genetic and environmental factors that can modify the rate of alcohol metabolism are discussed.
Copyright © 2012 Elsevier Inc. All rights reserved.

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Year:  2012        PMID: 23101976      PMCID: PMC3484320          DOI: 10.1016/j.cld.2012.08.002

Source DB:  PubMed          Journal:  Clin Liver Dis        ISSN: 1089-3261            Impact factor:   6.126


  69 in total

Review 1.  The P450 catalytic cycle and oxygenation mechanism.

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Journal:  Drug Metab Rev       Date:  1998-11       Impact factor: 4.518

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Authors:  G T Passananti; C A Wolff; E S Vesell
Journal:  Clin Pharmacol Ther       Date:  1990-03       Impact factor: 6.875

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Authors:  E R Gordon
Journal:  Can J Biochem       Date:  1972-09

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Authors:  C DiPadova; T M Worner; R J Julkunen; C S Lieber
Journal:  Gastroenterology       Date:  1987-05       Impact factor: 22.682

Review 5.  Genetic factors in alcohol metabolism and alcoholism.

Authors:  W F Bosron; T Ehrig; T K Li
Journal:  Semin Liver Dis       Date:  1993-05       Impact factor: 6.115

6.  Distribution of alcohol dehydrogenase and the low Km form of aldehyde dehydrogenase in isolated perivenous and periportal hepatocytes in rats.

Authors:  L Chen; R A Sidner; L Lumeng
Journal:  Alcohol Clin Exp Res       Date:  1992-02       Impact factor: 3.455

7.  Gender differences in the effects of ADH1B and ALDH2 polymorphisms on alcoholism.

Authors:  Mitsuru Kimura; Tomohiro Miyakawa; Sachio Matsushita; Mirai So; Susumu Higuchi
Journal:  Alcohol Clin Exp Res       Date:  2011-08-16       Impact factor: 3.455

Review 8.  P450 superfamily: update on new sequences, gene mapping, accession numbers and nomenclature.

Authors:  D R Nelson; L Koymans; T Kamataki; J J Stegeman; R Feyereisen; D J Waxman; M R Waterman; O Gotoh; M J Coon; R W Estabrook; I C Gunsalus; D W Nebert
Journal:  Pharmacogenetics       Date:  1996-02

9.  Factors that modify the metabolism of ethanol in rat liver and adaptive changes produced by its chronic administration.

Authors:  L Videla; Y Israel
Journal:  Biochem J       Date:  1970-06       Impact factor: 3.857

10.  Alcohol and acetaldehyde metabolism in Caucasians, Chinese and Amerinds.

Authors:  T E Reed; H Kalant; R J Gibbins; B M Kapur; J G Rankin
Journal:  Can Med Assoc J       Date:  1976-11-06       Impact factor: 8.262

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  261 in total

1.  Hepatobiliary Quiz (Answers)-15 (2015).

Authors:  Sahaj Rathi; Radha K Dhiman
Journal:  J Clin Exp Hepatol       Date:  2015-10-27

Review 2.  Structure, Function and Metabolism of Hepatic and Adipose Tissue Lipid Droplets: Implications in Alcoholic Liver Disease.

Authors:  Sathish Kumar Natarajan; Karuna Rasineni; Murali Ganesan; Dan Feng; Benita L McVicker; Mark A McNiven; Natalia A Osna; Justin L Mott; Carol A Casey; Kusum K Kharbanda
Journal:  Curr Mol Pharmacol       Date:  2017       Impact factor: 3.339

Review 3.  Role of CYP2E1 in Mitochondrial Dysfunction and Hepatic Injury by Alcohol and Non-Alcoholic Substances.

Authors:  Mohamed A Abdelmegeed; Seung-Kwon Ha; Youngshim Choi; Mohammed Akbar; Byoung-Joon Song
Journal:  Curr Mol Pharmacol       Date:  2017       Impact factor: 3.339

4.  Placental Proteomics Reveal Insights into Fetal Alcohol Spectrum Disorders.

Authors:  Katie L Davis-Anderson; Sebastian Berger; Emilie R Lunde-Young; Vishal D Naik; Heewon Seo; Greg A Johnson; Hanno Steen; Jayanth Ramadoss
Journal:  Alcohol Clin Exp Res       Date:  2017-08-09       Impact factor: 3.455

5.  Quantifying Competition among Mitochondrial Protein Acylation Events Induced by Ethanol Metabolism.

Authors:  Hadi R Ali; Mohammed A Assiri; Peter S Harris; Cole R Michel; Youngho Yun; John O Marentette; Frank K Huynh; David J Orlicky; Colin T Shearn; Laura M Saba; Richard Reisdorph; Nichole Reisdorph; Matthew D Hirschey; Kristofer S Fritz
Journal:  J Proteome Res       Date:  2019-01-31       Impact factor: 4.466

Review 6.  Extracellular matrix and liver disease.

Authors:  Elena Arriazu; Marina Ruiz de Galarreta; Francisco Javier Cubero; Marta Varela-Rey; María Pilar Pérez de Obanos; Tung Ming Leung; Aritz Lopategi; Aitor Benedicto; Ioana Abraham-Enachescu; Natalia Nieto
Journal:  Antioxid Redox Signal       Date:  2014-01-08       Impact factor: 8.401

7.  Zinc deficiency mediates alcohol-induced apoptotic cell death in the liver of rats through activating ER and mitochondrial cell death pathways.

Authors:  Qian Sun; Wei Zhong; Wenliang Zhang; Qiong Li; Xiuhua Sun; Xiaobing Tan; Xinguo Sun; Daoyin Dong; Zhanxiang Zhou
Journal:  Am J Physiol Gastrointest Liver Physiol       Date:  2015-03-12       Impact factor: 4.052

Review 8.  Enzymatic and nonenzymatic protein acetylations control glycolysis process in liver diseases.

Authors:  Juan Li; Tongxin Wang; Jun Xia; Weilei Yao; Feiruo Huang
Journal:  FASEB J       Date:  2019-08-01       Impact factor: 5.191

9.  Dietary Fisetin Supplementation Protects Against Alcohol-Induced Liver Injury in Mice.

Authors:  Qian Sun; Wenliang Zhang; Wei Zhong; Xinguo Sun; Zhanxiang Zhou
Journal:  Alcohol Clin Exp Res       Date:  2016-08-30       Impact factor: 3.455

Review 10.  r

Authors:  Jacqueline S Womersley; Danyelle M Townsend; Peter W Kalivas; Joachim D Uys
Journal:  Eur J Neurosci       Date:  2018-09-24       Impact factor: 3.386

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