Literature DB >> 2310181

Isoverrucarol production by Fusarium oxysporum CJS-12 isolated from corn.

K H Kim1, Y W Lee, C J Mirocha, R J Pawlosky.   

Abstract

Isoverrucarol (3,15-dihydroxy-12,13-epoxy-trichothec-9-ene) was isolated and purified from wheat cultures of a toxic strain of Fusarium oxysporum CJS-12. The toxin was characterized by thin-layer chromatography, gas chromatography-mass spectrometry, and 1H and 13C nuclear magnetic resonance spectrometry. Isoverrucarol caused toxic effects in rats, including loss of appetite, bodily weakness, severe mucosae of the stomach, and death, when administered orally at 10 and 20 mg/kg of body weight. The toxin also caused a definite dermatitic reaction of epidermis and an edematic-necrotic response of the dermis.

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Year:  1990        PMID： 2310181      PMCID： PMC183300          DOI： 10.1128/aem.56.1.260-263.1990

Source DB:  PubMed          Journal:  Appl Environ Microbiol        ISSN： 0099-2240            Impact factor:   4.792


  8 in total

1.  Biological properties of some toxic fungi isolated from overwintered cereals.

Authors:  A Z JOFFE
Journal:  Mycopathol Mycol Appl       Date:  1962-03-10

2.  Toxicological approaches to the metabolites of Fusaria. IV. Microbial survey on "bean-hulls poisoning of horses" with the isolation of toxic trichothecenes, neosolaniol and T-2 toxin of Fusarium solani M-1-1.

Authors:  Y Ueno; K Ishii; K Sakai; S Kanaeda; H Tsunoda
Journal:  Jpn J Exp Med       Date:  1972-06

3.  Biological and chemical detection of trichothecene mycotoxins of Fusarium species.

Authors:  Y Ueno; N Sato; K Ishii; K Sakai; H Tsunoda
Journal:  Appl Microbiol       Date:  1973-04

4.  Toxicologic studies of Fusarium tricinctum (Corda) Snyder et Hansen from moldy corn.

Authors:  N R Kosuri; E B Smalley; R E Nichols
Journal:  Am J Vet Res       Date:  1971-11       Impact factor: 1.156

5.  Spectrodensitometric determination of trichothecene mycotoxins with 4-(p-nitrobenzyl)pyridine on silica gel thin-layer chromatograms.

Authors:  S Takitani; Y Asabe; T Kato; M Suzuki; Y Ueno
Journal:  J Chromatogr       Date:  1979-04-21

6.  Fusariotoxicosis from barley in British Columbia. I. Natural occurrence and diagnosis.

Authors:  J A Greenway; R Puls
Journal:  Can J Comp Med       Date:  1976-01

7.  Trichothecenes accumulated in liquid culture of a mutant of Fusarium sporotrichioides NRRL 3299.

Authors:  R D Plattner; L W Tjarks; M N Beremand
Journal:  Appl Environ Microbiol       Date:  1989-09       Impact factor: 4.792

8.  Identification of T-2 toxin in moldy corn associated with a lethal toxicosis in dairy cattle.

Authors:  I C Hsu; E B Smalley; F M Strong; W E Ribelin
Journal:  Appl Microbiol       Date:  1972-11
  8 in total
  3 in total

1.  The phytotoxicity ofFusarium metabolites: An update since 1989.

Authors:  M McLean
Journal:  Mycopathologia       Date:  1996-03       Impact factor: 2.574

2.  A hemorrhagic factor (Apicidin) produced by toxic Fusarium isolates from soybean seeds.

Authors:  J S Park; K R Lee; J C Kim; S H Lim; J A Seo; Y W Lee
Journal:  Appl Environ Microbiol       Date:  1999-01       Impact factor: 4.792

3.  Natural occurrence of Fusarium mycotoxins (trichothecenes and zearalenone) in barley and corn in Korea.

Authors:  J C Kim; H J Kang; D H Lee; Y W Lee; T Yoshizawa
Journal:  Appl Environ Microbiol       Date:  1993-11       Impact factor: 4.792
  3 in total

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