Literature DB >> 23100971

Hard palate perforation in acute lymphoblastic leukemia due to mucormycosis - a case report.

Dipti R Samanta1, Surendra N Senapati, Praveen K Sharma, B S Shruthi, Prajna Bimoch Paty, Gitanjali Sarangi.   

Abstract

Palatal perforation can occur due to trauma, infection and malignancy. Mucormycosis is a rare opportunistic fungal infection caused by an organism of class zygomycetes. Rhinocerebral mucormycosis is the most common type of mucormycosis that typically starts in maxillary antrum in immunocompromised patients. Invasion of surrounding structures leads to necrotizing ulcer of the hard palate and ultimately leads to perforation. Here, we report a case of perforation of the hard palate due to mucormycosis in a eight years child having acute lymphoblastic leukemia (ALL), who was on prolonged chemotherapy and corticosteroid therapy. This case is being reported for its rarity. The aim of presenting this case report is to emphasize that the infection due to mucomycosis should be included in the differential diagnosis of hard palate perforation in ALL patients who are immunocompromised.

Entities:  

Keywords:  Acute lymphoblastic leukemia; Hard palate perforation; Immunocompromised; Mucormycosis

Year:  2009        PMID: 23100971      PMCID: PMC3453487          DOI: 10.1007/s12288-009-0009-3

Source DB:  PubMed          Journal:  Indian J Hematol Blood Transfus        ISSN: 0971-4502            Impact factor:   0.900


  16 in total

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2.  Epidemiology and outcome of mould infections in hematopoietic stem cell transplant recipients.

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4.  Mucormycosis: necrotizing soft tissue lesion of the face.

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Authors:  S Jayachandran; C Krithika
Journal:  Indian J Dent Res       Date:  2006 Jul-Sep

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Journal:  N Engl J Med       Date:  1971-03-25       Impact factor: 91.245

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Authors:  Bradley A Seyer; William Grist; Susan Muller
Journal:  Oral Surg Oral Med Oral Pathol Oral Radiol Endod       Date:  2002-10

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Authors:  J A Ribes; C L Vanover-Sams; D J Baker
Journal:  Clin Microbiol Rev       Date:  2000-04       Impact factor: 26.132

9.  Specific susceptibility to mucormycosis in murine diabetes and bronchoalveolar macrophage defense against Rhizopus.

Authors:  A R Waldorf; N Ruderman; R D Diamond
Journal:  J Clin Invest       Date:  1984-07       Impact factor: 14.808

10.  Localized mucormycosis following intramuscular corticosteroid. Case report and review of the literature.

Authors:  J K Jain; A Markowitz; P V Khilanani; C B Lauter
Journal:  Am J Med Sci       Date:  1978 Mar-Apr       Impact factor: 2.378

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  2 in total

1.  Oral mucormycosis in an 18-month-old child: a rare case report with a literature review.

Authors:  Ritesh Rambharos Kalaskar; Ashita Ritesh Kalaskar; Sindhu Ganvir
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2.  Prosthetic Management of Hard Palate Perforation in a Child with Acute Lymphoblastic Leukemia.

Authors:  Gunjan C Chouksey; Kanchan P Dholam
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  2 in total

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