OBJECTIVE: To evaluate the incidence of hereditary bleeding disorders, registered at our centre from all over Uttar Pradesh over an extended period of 10 years. MATERIAL AND METHODS: A complete coagulation profile of 240 cases conducted, followed by clinical history of the patient. The frequency and type of bleeding, age of onset, treatment taken, consanguinity and the blood transfusion if any, are little information collected from the patient. RESULTS: The complete scenario of bleeders indicated maximum number (92%) of hemophilia 'A' from northern UP as compared from other zones (76.5% ± 3). Contrarily, hemophilia 'B' registered maximum from eastern zone (26%) and minimum from the northern zone (8%). The age diversity at diagnosis ranged between 1-32 years. The reasons for difference are all speculative. Definite cause needs extensive research. CONCLUSIONS: The study showed that elderly patients with hemophilia had significantly more impairments in physical functioning and depression than younger ones.
OBJECTIVE: To evaluate the incidence of hereditary bleeding disorders, registered at our centre from all over Uttar Pradesh over an extended period of 10 years. MATERIAL AND METHODS: A complete coagulation profile of 240 cases conducted, followed by clinical history of the patient. The frequency and type of bleeding, age of onset, treatment taken, consanguinity and the blood transfusion if any, are little information collected from the patient. RESULTS: The complete scenario of bleeders indicated maximum number (92%) of hemophilia 'A' from northern UP as compared from other zones (76.5% ± 3). Contrarily, hemophilia 'B' registered maximum from eastern zone (26%) and minimum from the northern zone (8%). The age diversity at diagnosis ranged between 1-32 years. The reasons for difference are all speculative. Definite cause needs extensive research. CONCLUSIONS: The study showed that elderly patients with hemophilia had significantly more impairments in physical functioning and depression than younger ones.
Authors: Iris Plug; Eveline P Mauser-Bunschoten; Annette H J T Bröcker-Vriends; Hans Kristian Ploos van Amstel; Johanna G van der Bom; Joanna E M van Diemen-Homan; José Willemse; Frits R Rosendaal Journal: Blood Date: 2006-03-21 Impact factor: 22.113