Literature DB >> 23100862

A comparative study on the effects of Gemfibrozil, Diltiazem and Isosorbide dinitrate on lipid profile in patients of ischemic heart disease in India.

H O Sharma1, S K Sharma.   

Abstract

Effects of three drugs, Gemfibrozil, Diltiazem and lsosorbide dinitrate (ISDN) on various lipid parameters were studied in patients with ischemic heart disease (IHD) with positive treadmill stress response. Gemfibrozil and diltiazem significantly lowered the levels of serum total lipids (TL), triglycerides (TG), phospholipids (PL), total cholesterol (TC), low density lipoprotein cholesterol (LDL-C) and very low density lipoprotein cholesterol (VLDL-C), and incroased the levels of serum high density lipoprotein cholesterol (HDL-C) significantly. However, patients administered with ISDN showed a significant increase in all the lipid parameters except HDL-C, which showed a significant decrease.

Entities:  

Keywords:  Diltiazem; Gemfibrozil; Ischemic heart disease; Isosorbide dinitrate; Lipid profile

Year:  1997        PMID： 23100862      PMCID： PMC3454048          DOI： 10.1007/BF02867954

Source DB:  PubMed          Journal:  Indian J Clin Biochem        ISSN： 0970-1915


  13 in total

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Journal:  Am J Cardiol       Date:  1988-08-01       Impact factor: 2.778

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Journal:  Am J Cardiol       Date:  1985-12-06       Impact factor: 2.778

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Journal:  Am J Cardiol       Date:  1989-09-01       Impact factor: 2.778

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Authors:  R W Fenderson; S Deutsch; E Menachemi; B Chin; P Samuel
Journal:  Angiology       Date:  1982-09       Impact factor: 3.619

10.  Diverging effects of cholestyramine on apolipoprotein B and lipoprotein Lp(a). A dose-response study of the effects of cholestyramine in hypercholesterolaemia.

Authors:  B Vessby; G Kostner; H Lithell; J Thomis
Journal:  Atherosclerosis       Date:  1982-07       Impact factor: 5.162
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