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Literature DB >> 23100817

Human microbiomics.

Abstract

The sequencing of the human genome has driven the study of human biology in a significant way and enabled the genome-wide study to elucidate the molecular basis of complex human diseases. Recently, the role of microbiota on human physiology and health has received much attention. The influence of gut microbiome (the collective genomes of the gut microbiota) in obesity has been demonstrated, which may pave the way for new prophylactic and therapeutic strategies such as bacteriotherapy. The significance and recent understandings in the area of "human microbiomics" are discussed here.

Entities: Disease Species

Keywords: 16S rRNA; Bacteriotherapy; Human microbiome; Metagenomics; Microbial diversity; Obesity

Year: 2010 PMID： 23100817 PMCID： PMC3450280 DOI： 10.1007/s12088-010-0034-9

Source DB: PubMed Journal: Indian J Microbiol ISSN： 0046-8991 Impact factor: 2.461

22 in total

1. Genome sequence of E. coli O157:H7.

Authors: V Sperandio
Journal: Trends Microbiol Date: 2001-04 Impact factor: 17.079

2. Bacteriotherapy: the time has come.

Authors: P Huovinen
Journal: BMJ Date: 2001-08-18

3. Diversity of the human intestinal microbial flora.

Authors: Paul B Eckburg; Elisabeth M Bik; Charles N Bernstein; Elizabeth Purdom; Les Dethlefsen; Michael Sargent; Steven R Gill; Karen E Nelson; David A Relman
Journal: Science Date: 2005-04-14 Impact factor: 47.728

4. Single-cell genomics.

Authors: Clyde A Hutchison; J Craig Venter
Journal: Nat Biotechnol Date: 2006-06 Impact factor: 54.908

5. Molecular analysis of the bacterial microbiota in the human stomach.

Authors: Elisabeth M Bik; Paul B Eckburg; Steven R Gill; Karen E Nelson; Elizabeth A Purdom; Fritz Francois; Guillermo Perez-Perez; Martin J Blaser; David A Relman
Journal: Proc Natl Acad Sci U S A Date: 2006-01-04 Impact factor: 11.205

6. Metagenomic analysis of the human distal gut microbiome.

Authors: Steven R Gill; Mihai Pop; Robert T Deboy; Paul B Eckburg; Peter J Turnbaugh; Buck S Samuel; Jeffrey I Gordon; David A Relman; Claire M Fraser-Liggett; Karen E Nelson
Journal: Science Date: 2006-06-02 Impact factor: 47.728

7. Non-pathogenic Escherichia coli versus mesalazine for the treatment of ulcerative colitis: a randomised trial.

Authors: B J Rembacken; A M Snelling; P M Hawkey; D M Chalmers; A T Axon
Journal: Lancet Date: 1999-08-21 Impact factor: 79.321

8. Recolonization with selected alpha-streptococci for prophylaxis of recurrent streptococcal pharyngotonsillitis--a randomized placebo-controlled multicentre study.

Authors: K Roos; S E Holm; E Grahn-Håkansson; L Lagergren
Journal: Scand J Infect Dis Date: 1996

Human microbiomics.

1. Genome sequence of E. coli O157:H7.

2. Bacteriotherapy: the time has come.

3. Diversity of the human intestinal microbial flora.

4. Single-cell genomics.

5. Molecular analysis of the bacterial microbiota in the human stomach.

6. Metagenomic analysis of the human distal gut microbiome.

7. Non-pathogenic Escherichia coli versus mesalazine for the treatment of ulcerative colitis: a randomised trial.

8. Recolonization with selected alpha-streptococci for prophylaxis of recurrent streptococcal pharyngotonsillitis--a randomized placebo-controlled multicentre study.

9. Honor thy symbionts.

10. Obesity alters gut microbial ecology.

1. Fish Gut Microbiome: Current Approaches and Future Perspectives.

2. Only one health, and so many omics.