Literature DB >> 23100799

Pandemic swine influenza virus (H1N1): A threatening evolution.

Madhu Khanna1, Binod Kumar, Neha Gupta, Prashant Kumar, Ankit Gupta, V K Vijayan, Harpreet Kaur.   

Abstract

"Survival of the fittest" is an old axiom laid down by the great evolutionist Charles Darwin and microorganisms seem to have exploited this statement to a great extent. The ability of viruses to adapt themselves to the changing environment has made it possible to inhabit itself in this vast world for the past millions of years. Experts are well versed with the fact that influenza viruses have the capability to trade genetic components from one to the other within animal and human population. In mid April 2009, the Centers for Disease Control and Prevention and the World Health Organization had recognized a dramatic increase in number of influenza cases. These current 2009 infections were found to be caused by a new strain of influenza type A H1N1 virus which is a re-assortment of several strains of influenza viruses commonly infecting human, avian, and swine population. This evolution is quite dependent on swine population which acts as a main reservoir for the reassortment event in virus. With the current rate of progress and the efforts of heath authorities worldwide, we have still not lost the race against fighting this virus. This article gives an insight to the probable source of origin and the evolutionary progress it has gone through that makes it a potential threat in the future, the current scenario and the possible measures that may be explored to further strengthen the war against pandemic.

Entities:  

Keywords:  H1N1; Pandemic; Swine influenza virus

Year:  2010        PMID: 23100799      PMCID: PMC3450195          DOI: 10.1007/s12088-009-0064-3

Source DB:  PubMed          Journal:  Indian J Microbiol        ISSN: 0046-8991            Impact factor:   2.461


  14 in total

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Authors:  N N Zhou; D A Senne; J S Landgraf; S L Swenson; G Erickson; K Rossow; L Liu; K j Yoon; S Krauss; R G Webster
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Authors: 
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5.  Origin of the pandemic 1957 H2 influenza A virus and the persistence of its possible progenitors in the avian reservoir.

Authors:  J R Schäfer; Y Kawaoka; W J Bean; J Süss; D Senne; R G Webster
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6.  The Contribution of the PB1-F2 Protein to the Fitness of Influenza A Viruses and its Recent Evolution in the 2009 Influenza A (H1N1) Pandemic Virus.

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Authors:  Ann H Reid; Jeffery K Taubenberger
Journal:  J Gen Virol       Date:  2003-09       Impact factor: 3.891

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Authors: 
Journal:  MMWR Morb Mortal Wkly Rep       Date:  2009-05-01       Impact factor: 17.586

9.  The origin of the recent swine influenza A(H1N1) virus infecting humans.

Authors:  V Trifonov; H Khiabanian; B Greenbaum; R Rabadan
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Review 4.  Epidemic viral pneumonia and other emerging pathogens.

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Journal:  Clin Chest Med       Date:  2011-09       Impact factor: 2.878

5.  Study of oseltamivir and zanamivir resistance-related mutations in influenza viruses isolated from wild mallards in Sweden.

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