Literature DB >> 23100477

Preliminary evaluation of the safety and efficacy of standard intravenous immunoglobulins in pregnant women with primary cytomegalovirus infection.

Ennio Polilli1, Giustino Parruti, Francesca D'Arcangelo, Elisa Tracanna, Luigi Clerico, Vincenzo Savini, Francesco D'Antonio, Maurizio Rosati, Lamberto Manzoli, Domenico D'Antonio, Giovanni Nigro.   

Abstract

Hyperimmune globulins were reported to prevent and treat fetal cytomegalovirus (CMV) infection during pregnancy. Here, we report that infusions of standard human intravenous immunoglobulin significantly increase CMV IgG titers and avidity indexes in pregnant women, paving the way to their use for passive transfer of maternal CMV humoral immunity to fetuses. Preliminary data on perinatal outcomes of the first 67 newborns are encouraging.

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Year:  2012        PMID： 23100477      PMCID： PMC3535874          DOI： 10.1128/CVI.00509-12

Source DB:  PubMed          Journal:  Clin Vaccine Immunol        ISSN： 1556-679X


  19 in total

1.  Ability of three IgG-avidity assays to exclude recent cytomegalovirus infection.

Authors:  M Bodéus; D Beulné; P Goubau
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2001-04       Impact factor: 3.267

2.  Immunoglobulin therapy of fetal cytomegalovirus infection occurring in the first half of pregnancy--a case-control study of the outcome in children.

Authors:  Giovanni Nigro; Stuart P Adler; Giustino Parruti; Maurizio M Anceschi; Eleonora Coclite; Ilaria Pezone; Gian Carlo Di Renzo
Journal:  J Infect Dis       Date:  2011-12-02       Impact factor: 5.226

Review 3.  Mechanisms of action of intravenous immunoglobulin in autoimmune and inflammatory diseases.

Authors:  J Bayry; M Thirion; N Misra; N Thorenoor; S Delignat; S Lacroix-Desmazes; B Bellon; S Kaveri; M D Kazatchkine
Journal:  Neurol Sci       Date:  2003-10       Impact factor: 3.307

4.  Early primary cytomegalovirus infection in pregnancy: maternal hyperimmunoglobulin therapy improves outcomes among infants at 1 year of age.

Authors:  Silvia Visentin; Renzo Manara; Laura Milanese; Anna Da Roit; Gabriella Forner; Eleonora Salviato; Valentina Citton; Fioretta Marciani Magno; Eva Orzan; Carla Morando; Riccardo Cusinato; Carlo Mengoli; Giorgio Palu; Mario Ermani; Roberto Rinaldi; Erich Cosmi; Nadia Gussetti
Journal:  Clin Infect Dis       Date:  2012-04-26       Impact factor: 9.079

5.  Multicenter evaluation of a rapid and convenient method for determination of cytomegalovirus immunoglobulin G avidity.

Authors:  M Baccard-Longere; F Freymuth; D Cointe; J M Seigneurin; L Grangeot-Keros
Journal:  Clin Diagn Lab Immunol       Date:  2001-03

6.  Comparative evaluation of three automated systems for DNA extraction in conjunction with three commercially available real-time PCR assays for quantitation of plasma Cytomegalovirus DNAemia in allogeneic stem cell transplant recipients.

Authors:  Dayana Bravo; María Ángeles Clari; Elisa Costa; Beatriz Muñoz-Cobo; Carlos Solano; María José Remigia; David Navarro
Journal:  J Clin Microbiol       Date:  2011-06-22       Impact factor: 5.948

Review 7.  Intravenous immunoglobulins in immunodeficiencies: more than mere replacement therapy.

Authors:  S V Kaveri; M S Maddur; P Hegde; S Lacroix-Desmazes; J Bayry
Journal:  Clin Exp Immunol       Date:  2011-06       Impact factor: 4.330

8.  Use of cytomegalovirus hyperimmunoglobulin for prevention of congenital cytomegalovirus disease: a retrospective analysis.

Authors:  Horst Buxmann; Otto M v Stackelberg; Rolf L Schlößer; Gisela Enders; Markus Gonser; Matthias Meyer-Wittkopf; Klaus Hamprecht; Martin Enders
Journal:  J Perinat Med       Date:  2012-03-27       Impact factor: 1.901

9.  The value of immunoprophylaxis for cytomegalovirus infection with intravenous immunoglobulin in pediatric liver transplant recipients receiving a low-dose immunosupressive regimen.

Authors:  Katrin Krampe; Andrea Briem-Richter; Lutz Fischer; Bjoern Nashan; Rainer Ganschow
Journal:  Pediatr Transplant       Date:  2009-01-18

10.  Prevention of transfusion-acquired cytomegalovirus infections in newborn infants.

Authors:  A S Yeager; F C Grumet; E B Hafleigh; A M Arvin; J S Bradley; C G Prober
Journal:  J Pediatr       Date:  1981-02       Impact factor: 4.406
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  8 in total

1.  In Vitro Characterization of Human Cytomegalovirus-Targeting Therapeutic Monoclonal Antibodies LJP538 and LJP539.

Authors:  Hetalkumar D Patel; Pavel Nikitin; Thomas Gesner; James J Lin; David T Barkan; Claudio Ciferri; Andrea Carfi; Tahmineh Akbarnejad Yazdi; Peter Skewes-Cox; Brigitte Wiedmann; Nadine Jarousse; Weidong Zhong; Adam Feire; Christy M Hebner
Journal:  Antimicrob Agents Chemother       Date:  2016-07-22       Impact factor: 5.191

2.  Impact of Antibodies and Strain Polymorphisms on Cytomegalovirus Entry and Spread in Fibroblasts and Epithelial Cells.

Authors:  Xiaohong Cui; Daniel C Freed; Dai Wang; Ping Qiu; Fengsheng Li; Tong-Ming Fu; Lawrence M Kauvar; Michael A McVoy
Journal:  J Virol       Date:  2017-06-09       Impact factor: 5.103

Review 3.  The immunological underpinnings of vaccinations to prevent cytomegalovirus disease.

Authors:  A Louise McCormick; Edward S Mocarski
Journal:  Cell Mol Immunol       Date:  2014-12-29       Impact factor: 11.530

4.  Cytomegalovirus vaccine strain towne-derived dense bodies induce broad cellular immune responses and neutralizing antibodies that prevent infection of fibroblasts and epithelial cells.

Authors:  Corinne Cayatte; Kirsten Schneider-Ohrum; Zhaoti Wang; Alivelu Irrinki; Nga Nguyen; Janine Lu; Christine Nelson; Esteban Servat; Lorraine Gemmell; Andrzej Citkowicz; Yi Liu; Gregory Hayes; Jennifer Woo; Gary Van Nest; Hong Jin; Gregory Duke; A Louise McCormick
Journal:  J Virol       Date:  2013-08-07       Impact factor: 5.103

Review 5.  Cytomegalovirus in the neonate: immune correlates of infection and protection.

Authors:  Mark R Schleiss
Journal:  Clin Dev Immunol       Date:  2013-08-19

6.  T cell subsets and immunoglobulin G levels are associated with the infection status of systemic lupus erythematosus patients.

Authors:  Lifen Wu; Xinru Wang; Fenghua Chen; Xing Lv; Wenwen Sun; Ying Guo; Hou Hou; Haiyan Ji; Wei Wei; Lu Gong
Journal:  Braz J Med Biol Res       Date:  2017-12-11       Impact factor: 2.590

7.  Post-traumatic stress in pregnant women with primary cytomegalovirus infection and risk of congenital infection in newborns.

Authors:  Francesco Vadini; Elisa Tracanna; Ennio Polilli; Monica Tontodonati; Elena Ricci; Francesca Santilli; Giustino Parruti
Journal:  BJPsych Open       Date:  2016-11-24

Review 8.  Cytomegalovirus in pregnancy: to screen or not to screen.

Authors:  Susan P Walker; Ricardo Palma-Dias; Erica M Wood; Paul Shekleton; Michelle L Giles
Journal:  BMC Pregnancy Childbirth       Date:  2013-04-18       Impact factor: 3.007
  8 in total

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