Literature DB >> 23097576

Chiari malformation and central sleep apnoea: successful therapy with adaptive pressure support servo-ventilation following surgical treatment.

Ahmed Fahim1, Anthony O C Johnson.   

Abstract

Sleep apnoea is a common disorder with significant morbidity. It is categorised into obstructive and central sleep apnoea. There are a variety of conditions associated with central sleep apnoea ranging from cardiac failure to structural brain anomalies. We herein report a case of 57-year-old woman with Chiari malformation associated with significant sleep-disordered breathing. There was a family history of Chiari malformation. Although neurosurgical intervention had a significant impact on apnoea hypopnoea index (AHI) with a reduction from 81/h preoperatively to 22.1/h after the surgical treatment, it failed to cure the sleep disorder breathing completely and adaptive non-invasive servo-ventilation had a dramatic effect on symptoms and normalised the AHI. Although, central sleep apnoea is associated with a number of common disorders, this case illustrates that there may be an unusual cause. Moreover, adaptive pressure support servo-ventilation may provide a promising treatment option following surgical correction of Chiari malformation.

Entities:  

Mesh:

Year:  2012        PMID: 23097576      PMCID: PMC4543841          DOI: 10.1136/bcr-2012-007143

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  10 in total

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10.  Central sleep apnea is associated with increased ventilatory response to carbon dioxide and hypersecretion of growth hormone in patients with acromegaly.

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Journal:  Am J Respir Crit Care Med       Date:  1994-08       Impact factor: 21.405

  10 in total
  2 in total

1.  Chiari malformation and central sleep apnea syndrome: efficacy of treatment with adaptive servo-ventilation.

Authors:  Jorge Marques do Vale; Eloísa Silva; Isabel Gil Pereira; Catarina Marques; Amparo Sanchez-Serrano; António Simões Torres
Journal:  J Bras Pneumol       Date:  2014-10       Impact factor: 2.624

2.  A case of hypercapnic respiratory failure.

Authors:  Julie Van Woensel; Pieter Goeminne; Yvan Valcke
Journal:  Breathe (Sheff)       Date:  2021-03
  2 in total

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