Literature DB >> 23095636

Controversial aspects of oncogene-induced senescence.

Anna Bianchi-Smiraglia1, Mikhail A Nikiforov.   

Abstract

Oncogene-induced senescence (OIS) is a fail-safe mechanism that is developed to suppress cell proliferation caused by aberrant activation of oncoproteins in normal cells. Most of the available literature considers senescence to be caused by activated RAS or RAF proteins. In the current review, we will discuss some of the controversial aspects of RAS- or RAF-induced senescence in different types of normal cells: are tumor suppressors important for OIS? What is the role of DNA damage in OIS? Are there different types of OIS?

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Year:  2012        PMID： 23095636      PMCID： PMC3524210          DOI： 10.4161/cc.22589

Source DB:  PubMed          Journal:  Cell Cycle        ISSN： 1551-4005            Impact factor:   4.534


  107 in total

Review 1.  The many substrates and functions of ATM.

Authors:  M B Kastan; D S Lim
Journal:  Nat Rev Mol Cell Biol       Date:  2000-12       Impact factor: 94.444

Review 2.  Tumor suppressors and oncogenes in cellular senescence.

Authors:  F Bringold; M Serrano
Journal:  Exp Gerontol       Date:  2000-05       Impact factor: 4.032

Review 3.  Pathways of oncogene-induced senescence in human melanocytic cells.

Authors:  Rajat Bansal; Mikhail A Nikiforov
Journal:  Cell Cycle       Date:  2010-07-03       Impact factor: 4.534

4.  Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a.

Authors:  M Serrano; A W Lin; M E McCurrach; D Beach; S W Lowe
Journal:  Cell       Date:  1997-03-07       Impact factor: 41.582

Review 5.  Senescent cells, tumor suppression, and organismal aging: good citizens, bad neighbors.

Authors:  Judith Campisi
Journal:  Cell       Date:  2005-02-25       Impact factor: 41.582

6.  How to track cellular aging of mesenchymal stromal cells?

Authors:  Wolfgang Wagner; Simone Bork; Günther Lepperdinger; Sylvia Joussen; Nan Ma; Dirk Strunk; Carmen Koch
Journal:  Aging (Albany NY)       Date:  2010-04       Impact factor: 5.682

7.  Another "Janus paradox" of p53: induction of cell senescence versus quiescence.

Authors:  Zbigniew Darzynkiewicz
Journal:  Aging (Albany NY)       Date:  2010-06       Impact factor: 5.682

8.  mTOR and its link to the picture of Dorian Gray - re-activation of mTOR promotes aging.

Authors:  Józefa Wesierska-Gadek
Journal:  Aging (Albany NY)       Date:  2010-12       Impact factor: 5.682

9.  Depletion of Ku70/80 reduces the levels of extrachromosomal telomeric circles and inhibits proliferation of ALT cells.

Authors:  Baomin Li; Sita Reddy; Lucio Comai
Journal:  Aging (Albany NY)       Date:  2011-04       Impact factor: 5.682

10.  DNA damaging agents and p53 do not cause senescence in quiescent cells, while consecutive re-activation of mTOR is associated with conversion to senescence.

Authors:  Olga V Leontieva; Mikhail V Blagosklonny
Journal:  Aging (Albany NY)       Date:  2010-12       Impact factor: 5.682
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  20 in total

1.  Induction of accelerated senescence by the microtubule-stabilizing agent peloruside A.

Authors:  Ariane Chan; Connie Gilfillan; Nikki Templeton; Ian Paterson; Peter T Northcote; John H Miller
Journal:  Invest New Drugs       Date:  2017-07-22       Impact factor: 3.850

2.  Detection of Nucleotide Disbalance in Cells Undergoing Oncogene-Induced Senescence.

Authors:  Mikhail A Nikiforov; Donna S Shewach
Journal:  Methods Mol Biol       Date:  2017

Review 3.  The Immortal Senescence.

Authors:  Anna Bianchi-Smiraglia; Brittany C Lipchick; Mikhail A Nikiforov
Journal:  Methods Mol Biol       Date:  2017

4.  Multidrug resistance protein 3 loss promotes tumor formation by inducing senescence escape.

Authors:  C Wiel; B Gras; D Vindrieux; M Warnier; D Gitenay; B Le Calvé; M Ferrand; A Augert; D Bernard
Journal:  Oncogene       Date:  2015-06-15       Impact factor: 9.867

Review 5.  Emerging roles of the p38 MAPK and PI3K/AKT/mTOR pathways in oncogene-induced senescence.

Authors:  Yingxi Xu; Na Li; Rong Xiang; Peiqing Sun
Journal:  Trends Biochem Sci       Date:  2014-05-09       Impact factor: 13.807

6.  Tumor suppressor p16INK4A is necessary for survival of cervical carcinoma cell lines.

Authors:  Margaret E McLaughlin-Drubin; Donglim Park; Karl Munger
Journal:  Proc Natl Acad Sci U S A       Date:  2013-09-17       Impact factor: 11.205

7.  Oncogene-Induced Senescence in Pituitary Adenomas--an Immunohistochemical Study.

Authors:  Emilija Manojlovic-Gacic; Milica Skender-Gazibara; Vera Popovic; Ivan Soldatovic; Novica Boricic; Savo Raicevic; Sandra Pekic; Mirjana Doknic; Dragana Miljic; Irina Alafuzoff; Fredrik Pontén; Olivera Casar-Borota
Journal:  Endocr Pathol       Date:  2016-03       Impact factor: 3.943

Review 8.  Ras signaling through RASSF proteins.

Authors:  Howard Donninger; M Lee Schmidt; Jessica Mezzanotte; Thibaut Barnoud; Geoffrey J Clark
Journal:  Semin Cell Dev Biol       Date:  2016-06-08       Impact factor: 7.727

Review 9.  The DNA-damage response and nuclear events as regulators of nonapoptotic forms of cell death.

Authors:  Evgeniia A Prokhorova; Aleksandra Yu Egorshina; Boris Zhivotovsky; Gelina S Kopeina
Journal:  Oncogene       Date:  2019-08-28       Impact factor: 9.867

10.  NORE1A is a Ras senescence effector that controls the apoptotic/senescent balance of p53 via HIPK2.

Authors:  Howard Donninger; Diego F Calvisi; Thibaut Barnoud; Jennifer Clark; M Lee Schmidt; Michele D Vos; Geoffrey J Clark
Journal:  J Cell Biol       Date:  2015-03-16       Impact factor: 10.539
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