OBJECTIVES: Intention tremor becomes evident only when patients intend to move their body and is characterized by dysmetria. We have developed an on-demand control system that triggers the switching on/off of deep brain stimulation (DBS) instantly for the control of intention tremor. MATERIAL AND METHODS: We used surface electrodes for the recording of electromyographic (EMG) activity, and the power of EMG activity was analyzed instantly employing the fast Fourier transform. The on-demand control system switched on DBS when only the power of tremor frequency exceeded the on-trigger threshold, and the system switched off DBS when the total power of EMG activity decreased below the off-trigger threshold. RESULTS: The on-demand control system triggered the switching on/off of DBS accurately, and controlled intention tremor completely. Our on-demand control system is small and portable, and suitable for clinical use. CONCLUSIONS: The on-demand control system for DBS is useful for controlling intention tremor and may decrease the incidence of tolerance to DBS and may be a powerful tool for various applications of neuromodulation therapy.
OBJECTIVES: Intention tremor becomes evident only when patients intend to move their body and is characterized by dysmetria. We have developed an on-demand control system that triggers the switching on/off of deep brain stimulation (DBS) instantly for the control of intention tremor. MATERIAL AND METHODS: We used surface electrodes for the recording of electromyographic (EMG) activity, and the power of EMG activity was analyzed instantly employing the fast Fourier transform. The on-demand control system switched on DBS when only the power of tremor frequency exceeded the on-trigger threshold, and the system switched off DBS when the total power of EMG activity decreased below the off-trigger threshold. RESULTS: The on-demand control system triggered the switching on/off of DBS accurately, and controlled intention tremor completely. Our on-demand control system is small and portable, and suitable for clinical use. CONCLUSIONS: The on-demand control system for DBS is useful for controlling intention tremor and may decrease the incidence of tolerance to DBS and may be a powerful tool for various applications of neuromodulation therapy.
Authors: Jane E Huggins; Christoph Guger; Brendan Allison; Charles W Anderson; Aaron Batista; Anne-Marie A-M Brouwer; Clemens Brunner; Ricardo Chavarriaga; Melanie Fried-Oken; Aysegul Gunduz; Disha Gupta; Andrea Kübler; Robert Leeb; Fabien Lotte; Lee E Miller; Gernot Müller-Putz; Tomasz Rutkowski; Michael Tangermann; David Edward Thompson Journal: Brain Comput Interfaces (Abingdon) Date: 2014-01
Authors: Adam O Hebb; Jun Jason Zhang; Mohammad H Mahoor; Christos Tsiokos; Charles Matlack; Howard Jay Chizeck; Nader Pouratian Journal: Neurosurg Clin N Am Date: 2013-10-23 Impact factor: 2.509
Authors: Frédéric D Broccard; Tim Mullen; Yu Mike Chi; David Peterson; John R Iversen; Mike Arnold; Kenneth Kreutz-Delgado; Tzyy-Ping Jung; Scott Makeig; Howard Poizner; Terrence Sejnowski; Gert Cauwenberghs Journal: Ann Biomed Eng Date: 2014-05-15 Impact factor: 3.934
Authors: Pedram Afshar; Ankit Khambhati; Scott Stanslaski; David Carlson; Randy Jensen; Dave Linde; Siddharth Dani; Maciej Lazarewicz; Peng Cong; Jon Giftakis; Paul Stypulkowski; Tim Denison Journal: Front Neural Circuits Date: 2013-01-22 Impact factor: 3.492
Authors: Shenghong He; Jean Debarros; Saed Khawaldeh; Alek Pogosyan; Abteen Mostofi; Fahd Baig; Erlick Pereira; Peter Brown; Huiling Tan Journal: Annu Int Conf IEEE Eng Med Biol Soc Date: 2020-07