Literature DB >> 23093447

Temporal and spatial expression of KIF3B after acute spinal cord injury in adult rats.

Xiaowei Yu1, Hai Wen, Jianhua Cao, Binbin Sun, Tao Ding, Ming Li, Hao Wu, Long Long, Xinghai Cheng, Guangfei Xu, Feng Zhang.   

Abstract

The KIF3 subunit KIF3B was proved to be associated with mitosis. It has been known to be engaged in intracellular transport of neurons. To elucidate the certain expression and biological function in central nervous system, we performed an acute spinal cord contusion injury model in adult rats. Western blot analysis indicated a marked upregulation of KIF3B after spinal cord injury (SCI). Immunohistochemistry revealed wide distribution of KIF3B in spinal cord, including neurons and glial cells. Double immunofluorescent staining for proliferating cell nuclear antigen and phenotype-specific markers showed increases of KIF3B expression in proliferating microglia and astrocytes. Our data suggest that KIF3B may be implicated in the proliferation of microglia and astrocytes after SCI.

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Year:  2012        PMID： 23093447     DOI： 10.1007/s12031-012-9901-7

Source DB:  PubMed          Journal:  J Mol Neurosci        ISSN： 0895-8696            Impact factor:   3.444


  39 in total

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  9 in total

1.  KIF2A characterization after spinal cord injury.

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Journal:  Cell Mol Life Sci       Date:  2019-04-30       Impact factor: 9.261

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3.  Increased Expression of TBP/TFIID after spinal cord injury in adult rats.

Authors:  Tao Ding; Hai Wen; Haixiang Wei; Hao Wu; Jinlong Zhao; Fangyi Chen; Jian Zhao
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Authors:  Wei Zhou; Tongzhou Yuan; Youshui Gao; Peipei Yin; Wei Liu; Chenhao Pan; Yingjie Liu; Xiaowei Yu
Journal:  J Neurophysiol       Date:  2017-03-15       Impact factor: 2.714

5.  Wogonin protects rat dorsal root ganglion neurons against tunicamycin-induced ER stress through the PERK-eIF2α-ATF4 signaling pathway.

Authors:  Fangyi Chen; Rongbo Wu; Zhu Zhu; Wangping Yin; Min Xiong; Jianwei Sun; Miaozhong Ni; Guoping Cai; Xinchao Zhang
Journal:  J Mol Neurosci       Date:  2014-11-23       Impact factor: 3.444

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Journal:  J Mol Neurosci       Date:  2015-05-10       Impact factor: 3.444

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Authors:  Ziyang Shen; Hemin Jiang; Hsiang-Ting Hsu; Li Qian; Qi Fu; Min Shen; Shu Chen; Tao Yang
Journal:  Aging (Albany NY)       Date:  2019-03-01       Impact factor: 5.682

8.  Suppression of KIF3B expression inhibits human hepatocellular carcinoma proliferation.

Authors:  Xiaodong Huang; Fang Liu; Changlai Zhu; Jing Cai; Hua Wang; Xinxiu Wang; Song He; Cheng Liu; Li Yao; Zongmei Ding; Yixin Zhang; Tianyi Zhang
Journal:  Dig Dis Sci       Date:  2013-12-25       Impact factor: 3.199

9.  Circular RNA circ_0032462 Enhances Osteosarcoma Cell Progression by Promoting KIF3B Expression.

Authors:  Rui Gu; Xiaodong Li; Xiaowei Yan; Zhen Feng; Aixin Hu
Journal:  Technol Cancer Res Treat       Date:  2020 Jan-Dec
  9 in total

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