Filip Lindahl1, Erik Tesselaar, Folke Sjöberg. 1. Department of Clinical and Experimental Medicine, Faculty of Health Sciences, Linköping University, SE-58185 Linköping, Sweden.
Abstract
BACKGROUND: The use of objective methods for assessment of burns is limited. Laser Speckle Contrast Imaging (LSCI) is a non-invasive technique for instant measurement of tissue perfusion, making it potentially valuable for early prediction of burn wound outcome. AIM: To evaluate the influence of technical factors on perfusion and to measure perfusion in burns 0-14 days post-burn and compare this with the outcome of the burn wound at 14 days after burn. METHOD: The effect of room light, camera distance and camera angle was studied using a suspension of polystyrene particles. LSCI measurements were performed on 45 scald burns and 32 uninjured areas 0-14 days after burn. RESULT: Technical factors had no clinically relevant effect on measured perfusion. Burns that healed within 14 days had a higher perfusion during the first week post-burn than burns that healed after 14 days or underwent surgery. The difference in perfusion was largest 4-7 days after burn. CONCLUSION: LSCI allows for robust, instant measurement of burns and can easily be applied in a clinical setting. Differences in perfusion during the first week post-burn are related to the outcome after 14 days.
BACKGROUND: The use of objective methods for assessment of burns is limited. Laser Speckle Contrast Imaging (LSCI) is a non-invasive technique for instant measurement of tissue perfusion, making it potentially valuable for early prediction of burn wound outcome. AIM: To evaluate the influence of technical factors on perfusion and to measure perfusion in burns 0-14 days post-burn and compare this with the outcome of the burn wound at 14 days after burn. METHOD: The effect of room light, camera distance and camera angle was studied using a suspension of polystyrene particles. LSCI measurements were performed on 45 scald burns and 32 uninjured areas 0-14 days after burn. RESULT: Technical factors had no clinically relevant effect on measured perfusion. Burns that healed within 14 days had a higher perfusion during the first week post-burn than burns that healed after 14 days or underwent surgery. The difference in perfusion was largest 4-7 days after burn. CONCLUSION: LSCI allows for robust, instant measurement of burns and can easily be applied in a clinical setting. Differences in perfusion during the first week post-burn are related to the outcome after 14 days.
Authors: Christian Crouzet; John Quan Nguyen; Adrien Ponticorvo; Nicole P Bernal; Anthony J Durkin; Bernard Choi Journal: Burns Date: 2015-03-24 Impact factor: 2.744
Authors: Jeffrey E Thatcher; John J Squiers; Stephen C Kanick; Darlene R King; Yang Lu; Yulin Wang; Rachit Mohan; Eric W Sellke; J Michael DiMaio Journal: Adv Wound Care (New Rochelle) Date: 2016-08-01 Impact factor: 4.730