Kristin M Knight1, Loralei L Thornburg, Eva K Pressman. 1. Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, University of Rochester Strong Memorial Hospital, Rochester, New York, USA. kristinmaeknight@gmail.com
Abstract
OBJECTIVE: To characterize the neonatal and maternal outcomes of type 2 diabetic patients as compared with type 1 diabetic patients and nondiabetic controls. STUDY DESIGN: We performed a retrospective cohort study reviewing perinatal outcomes of type 1 and type 2 diabetic patients and nondiabetic controls from July 2000 to August 2006. Analysis of variance, t testing and chi2 analysis were used to compare groups. Post hoc power analysis indicated 80% power was necessary to detect a 15% difference in composite poor neonatal outcomes. RESULTS: A total of 64 type 2 and 64 type 1 diabetic patients were compared with 256 controls. Type 1 diabetic patients had higher incidences of composite poor neonatal outcome and congenital anomalies than did type 2 diabetic and control patients. Both diabetic groups had similarly higher incidences of cesarean delivery, preeclampsia, preterm delivery, polyhydramnios and macrosomia than did controls. CONCLUSION: Type 2 diabetic patients have a decreased incidence of adverse neonatal outcomes when compared with that of type 1 diabetic patients. No difference was observed between the diabetic groups in the incidence of a majority of the adverse maternal outcomes examined, however both diabetic groups had overall worse outcomes that did nondiabetic controls.
OBJECTIVE: To characterize the neonatal and maternal outcomes of type 2 diabeticpatients as compared with type 1 diabeticpatients and nondiabetic controls. STUDY DESIGN: We performed a retrospective cohort study reviewing perinatal outcomes of type 1 and type 2 diabeticpatients and nondiabetic controls from July 2000 to August 2006. Analysis of variance, t testing and chi2 analysis were used to compare groups. Post hoc power analysis indicated 80% power was necessary to detect a 15% difference in composite poor neonatal outcomes. RESULTS: A total of 64 type 2 and 64 type 1 diabeticpatients were compared with 256 controls. Type 1 diabeticpatients had higher incidences of composite poor neonatal outcome and congenital anomalies than did type 2 diabetic and control patients. Both diabetic groups had similarly higher incidences of cesarean delivery, preeclampsia, preterm delivery, polyhydramnios and macrosomia than did controls. CONCLUSION:Type 2 diabeticpatients have a decreased incidence of adverse neonatal outcomes when compared with that of type 1 diabeticpatients. No difference was observed between the diabetic groups in the incidence of a majority of the adverse maternal outcomes examined, however both diabetic groups had overall worse outcomes that did nondiabetic controls.
Authors: Amal Al Serehi; Amjad M Ahmed; Farah Shakeel; Khadija Alkhatani; Nahid K El-Bakri; Badr Aldin M Buhari; Uhoud Al Mohareb; Naji Aljohani Journal: Int J Clin Exp Med Date: 2015-07-15
Authors: Dana Dabelea; Katherine A Sauder; Elizabeth T Jensen; Amy K Mottl; Alyssa Huang; Catherine Pihoker; Richard F Hamman; Jean Lawrence; Lawrence M Dolan; Ralph D' Agostino; Lynne Wagenknecht; Elizabeth J Mayer-Davis; Santica M Marcovina Journal: Ann N Y Acad Sci Date: 2021-02-05 Impact factor: 6.499