Literature DB >> 23091583

Post-Irradiation Morphea: Case report and review of the literature.

Ammar Alhathlool1, Rüdiger Hein, Christian Andres, Johannes Ring, Bernadette Eberlein.   

Abstract

BACKGROUND: Post-irradiation morphea (PIM) is an entity documented in the literature although still not mentioned in most of the dermatological textbooks with a frequency approximately 2 out of every 1000 patients who received radiotherapy. Most of the cases are misdiagnosed as recurrent or metastatic carcinoma. MAIN OBSERVATIONS: We report on a 64-year-old woman who was treated with radiotherapy for breast cancer. Two years and eight months after the first dose of radiotherapy, she developed localized morphea in the irradiated area.
CONCLUSION: We report on a new case with a literature review and discuss pathogenesis, treatment modalities and post irradiation subcutaneos reactions mimicking PIM. Around 54 cases of post-irradiation morphea (PIM) were identified in the literature.

Entities:  

Keywords:  adverse event; morphea; radiation; scleroderma

Year:  2012        PMID: 23091583      PMCID: PMC3470793          DOI: 10.3315/jdcr.2012.1106

Source DB:  PubMed          Journal:  J Dermatol Case Rep        ISSN: 1898-7249


  36 in total

1.  [Radiation-induced morphea].

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2.  A randomized controlled study of low-dose UVA1, medium-dose UVA1, and narrowband UVB phototherapy in the treatment of localized scleroderma.

Authors:  Alexander Kreuter; Julia Hyun; Markus Stücker; Anna Sommer; Peter Altmeyer; Thilo Gambichler
Journal:  J Am Acad Dermatol       Date:  2006-01-30       Impact factor: 11.527

3.  Successful ultraviolet A1 phototherapy in the treatment of localized scleroderma: a retrospective and prospective study.

Authors:  C Andres; A Kollmar; M Mempel; R Hein; J Ring; B Eberlein
Journal:  Br J Dermatol       Date:  2009-08-08       Impact factor: 9.302

Review 4.  Postirradiation morphea of the breast presentation of two cases and review of the literature.

Authors:  J V Schaffer; C Carroll; I Dvoretsky; M J Huether; M Girardi
Journal:  Dermatology       Date:  2000       Impact factor: 5.366

5.  Postirradiation morphea in a breast cancer patient.

Authors:  Steve Dubner; Joseph Bovi; Julia White; Barbara Susnik
Journal:  Breast J       Date:  2006 Mar-Apr       Impact factor: 2.431

Review 6.  Pseudosclerodermatous panniculitis after irradiation: an unusual complication of megavoltage treatment of breast carcinoma.

Authors:  R K Winkelmann; G L Grado; S R Quimby; S M Connolly
Journal:  Mayo Clin Proc       Date:  1993-02       Impact factor: 7.616

Review 7.  Mixed connective tissue disease and radiation toxicity. A case report.

Authors:  N A Mayr; C E Riggs; K G Saag; B C Wen; E C Pennington; D H Hussey
Journal:  Cancer       Date:  1997-02-01       Impact factor: 6.860

Review 8.  Skin toxicity during breast irradiation: pathophysiology and management.

Authors:  Jennifer L Harper; Lynette E Franklin; Joseph M Jenrette; Eric G Aguero
Journal:  South Med J       Date:  2004-10       Impact factor: 0.954

9.  Postirradiation linear morphoea.

Authors:  B N Akay; H Sanli; A O Heper
Journal:  Clin Exp Dermatol       Date:  2009-10-23       Impact factor: 3.470

10.  Imaging surveillance of the breast in a patient diagnosed with scleroderma after breast-conserving surgery and radiotherapy.

Authors:  Melanie Seale; Wan Koh; Michael Henderson; Roslyn Drummond; Jennifer Cawson
Journal:  Breast J       Date:  2008 Jul-Aug       Impact factor: 2.431

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  6 in total

1.  Is it really post-irradiation morphea or oleoma of the breast?-A case report and literature review.

Authors:  Han Shin Lee; Eun Jung Jung; Jae Myung Kim; Ju Yeon Kim; In Kyeong Kim; Jae Ri Kim; Tae Han Kim; Jae Yool Jang; Jung Woo Woo; JinKwon Lee; Taejin Park; Sang Ho Jeong; Eun Cho; Hyo Jung An
Journal:  Gland Surg       Date:  2021-12

2.  A case of radiation-induced generalized morphea with prominent mucin deposition and tenderness.

Authors:  Koichi Yanaba; Yoshinori Umezawa; Hidemi Nakagawa
Journal:  Am J Case Rep       Date:  2015-05-10

3.  Post-Irradiation Morphea of the Breast in a Patient with Subacute Cutaneous Lupus Erythematosus: Case Report and a Literature Review.

Authors:  Carole Anouk Zahn; Laurence Feldmeyer; Roland Blum; Carlo Mainetti
Journal:  Case Rep Dermatol       Date:  2022-05-30

4.  Incidence of Morphea following Adjuvant Irradiation of the Breast in 2,268 Patients.

Authors:  Richard Partl; Peter Regitnig; Katarzyna Lukasiak; Peter Winkler; Karin Sigrid Kapp
Journal:  Breast Care (Basel)       Date:  2019-08-16       Impact factor: 2.860

5.  Radiation-induced morphea-a rare but severe late effect of adjuvant breast irradiation : Case report and review of the literature.

Authors:  Richard Partl; Peter Regitnig; Gerlinde Tauber; Michaela Pötscher; Vesna Bjelic-Radisic; Karin S Kapp
Journal:  Strahlenther Onkol       Date:  2018-07-16       Impact factor: 3.621

Review 6.  Intriguing Relationships Between Cancer and Systemic Sclerosis: Role of the Immune System and Other Contributors.

Authors:  Alexandre Thibault Jacques Maria; Léo Partouche; Radjiv Goulabchand; Sophie Rivière; Pauline Rozier; Céline Bourgier; Alain Le Quellec; Jacques Morel; Danièle Noël; Philippe Guilpain
Journal:  Front Immunol       Date:  2019-01-10       Impact factor: 7.561

  6 in total

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