| Literature DB >> 23088773 |
Giorgio Abbiati1, Arjana Doda, Monica Dell'Acqua, Valentina Pirovano, Diego Facoetti, Silvia Rizzato, Elisabetta Rossi.
Abstract
Two unprecedented oxygenated aaptaminoids have been synthesized starting from cheap and easily available 2,3-dihydroxybenzoic acid with the satisfactory overall yields of 31% and 34%. The key step of the procedure is the divergent thermic 5-exodig vs base-promoted 6-endodig cyclization of a 5-alkynylquinolinone derivative.Entities:
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Year: 2012 PMID: 23088773 DOI: 10.1021/jo3020598
Source DB: PubMed Journal: J Org Chem ISSN: 0022-3263 Impact factor: 4.354