Literature DB >> 23087723

"Excess gooD can be Dangerous". A case series of iatrogenic symptomatic hypercalcemia due to hypervitaminosis D.

Kamal Kishore Pandita1, Sushil Razdan, Rattan Parkash Kudyar, Aadil Beigh, Shafi Kuchay, Tanveer Banday.   

Abstract

Vitamin D is increasingly recognized to have several beneficial effects. Its toxicity, causing hypercalcemia, is considered as extremely rare. We report case series of 15 patients (most of them being elderly subjects) with iatrogenic symptomatic hypercalcemia in whom toxicity occurred due to empirical excessive administration of vitamin D by oral and parenteral route.

Entities:  

Keywords:  elderly patients; hypercalcemia; hypervitaminosis D; iatrogenic; vitamin D toxicity

Year:  2012        PMID： 23087723      PMCID： PMC3476516     

Source DB:  PubMed          Journal:  Clin Cases Miner Bone Metab        ISSN： 1724-8914


  6 in total

Review 1.  Vitamin D deficiency.

Authors:  Michael F Holick
Journal:  N Engl J Med       Date:  2007-07-19       Impact factor: 91.245

Review 2.  Pharmacokinetics of vitamin D toxicity.

Authors:  Glenville Jones
Journal:  Am J Clin Nutr       Date:  2008-08       Impact factor: 7.045

Review 3.  Fracture prevention with vitamin D supplementation: a meta-analysis of randomized controlled trials.

Authors:  Heike A Bischoff-Ferrari; Walter C Willett; John B Wong; Edward Giovannucci; Thomas Dietrich; Bess Dawson-Hughes
Journal:  JAMA       Date:  2005-05-11       Impact factor: 56.272

4.  "Toxic" beef bone soup.

Authors:  Kamal Kishore Pandita; Sarla Pandita; Tanveer Hassan
Journal:  Clin Cases Miner Bone Metab       Date:  2011-05

5.  Independent association of low serum 25-hydroxyvitamin d and 1,25-dihydroxyvitamin d levels with all-cause and cardiovascular mortality.

Authors:  Harald Dobnig; Stefan Pilz; Hubert Scharnagl; Wilfried Renner; Ursula Seelhorst; Britta Wellnitz; Jürgen Kinkeldei; Bernhard O Boehm; Gisela Weihrauch; Winfried Maerz
Journal:  Arch Intern Med       Date:  2008-06-23

6.  Hypervitaminosis D associated with drinking milk.

Authors:  C H Jacobus; M F Holick; Q Shao; T C Chen; I A Holm; J M Kolodny; G E Fuleihan; E W Seely
Journal:  N Engl J Med       Date:  1992-04-30       Impact factor: 91.245
  6 in total
  13 in total

Review 1.  Skin, reactive oxygen species, and circadian clocks.

Authors:  Mary A Ndiaye; Minakshi Nihal; Gary S Wood; Nihal Ahmad
Journal:  Antioxid Redox Signal       Date:  2013-11-21       Impact factor: 8.401

Review 2.  A review of the growing risk of vitamin D toxicity from inappropriate practice.

Authors:  Peter N Taylor; J Stephen Davies
Journal:  Br J Clin Pharmacol       Date:  2018-04-16       Impact factor: 4.335

3.  The changing profile of hypercalcemia in a tertiary care setting in North India: an 18-month retrospective study.

Authors:  Mohammad Shafi Kuchay; Parjeet Kaur; Sunil Kumar Mishra; Ambrish Mithal
Journal:  Clin Cases Miner Bone Metab       Date:  2017-10-25

4.  RISK OF HYPERCALCEMIA IN ELDERLY PATIENTS WITH HYPERVITAMINOSIS D AND INTOXICATION.

Authors:  A Batman; Y Altuntas
Journal:  Acta Endocrinol (Buchar)       Date:  2021 Apr-Jun       Impact factor: 0.877

5.  Primary vitamin D target genes allow a categorization of possible benefits of vitamin D₃ supplementation.

Authors:  Carsten Carlberg; Sabine Seuter; Vanessa D F de Mello; Ursula Schwab; Sari Voutilainen; Kari Pulkki; Tarja Nurmi; Jyrki Virtanen; Tomi-Pekka Tuomainen; Matti Uusitupa
Journal:  PLoS One       Date:  2013-07-29       Impact factor: 3.240

6.  Hyper Vitaminosis D: Are we Overprescribing Vitamin D?

Authors:  R Hemachandar; Lokesh Shanmugam; Balakrishna Malepati; Suresh Venugopal
Journal:  J Family Med Prim Care       Date:  2014 Oct-Dec

7.  Vitamin D toxicity in a pediatric toxicological referral center; a cross-sectional study from Iran.

Authors:  Fariba Farnaghi; Hossein Hassanian-Moghaddam; Nasim Zamani; Narges Gholami; Latif Gachkar; Maryam Hosseini Yazdi
Journal:  BMC Pediatr       Date:  2020-07-20       Impact factor: 2.125

8.  Iatrogenic hypervitaminosis D as an unusual cause of persistent vomiting: a case report.

Authors:  Rinkesh Kumar Bansal; Pankaj Tyagi; Praveen Sharma; Vikas Singla; Veronica Arora; Naresh Bansal; Ashish Kumar; Anil Arora
Journal:  J Med Case Rep       Date:  2014-02-26

Review 9.  Development of Vitamin D Toxicity from Overcorrection of Vitamin D Deficiency: A Review of Case Reports.

Authors:  Kornelia Galior; Stefan Grebe; Ravinder Singh
Journal:  Nutrients       Date:  2018-07-24       Impact factor: 5.717

10.  Redundancy Is of No Good; Iatrogenic Hypervitaminosis D: A Rare Case of Persistent Vomiting Due to Hypercalcemia.

Authors:  Muhammad Ishaq Ghauri; Syeda Beenish Bareeqa; Amir Riaz; Ajeet Kumar
Journal:  Clin Med Insights Case Rep       Date:  2019-02-07
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