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Literature DB >> 23086120

Mechanisms behind the increased vulnerability of the aging stomach to NSAID-related injury: perhaps not as simple as we may think.

Raymond S Tang, Francis K L Chan.

Abstract

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Year: 2013 PMID： 23086120 DOI： 10.1007/s10620-012-2443-6

Source DB: PubMed Journal: Dig Dis Sci ISSN： 0163-2116 Impact factor: 3.199

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18 in total

1. Effect of aging on gastric mucosal defense mechanisms: ROS, apoptosis, angiogenesis, and sensory neurons.

Authors: Jung Mook Kang; Nayoung Kim; Joo-Hyon Kim; Euichaul Oh; Bong-Yong Lee; Byoung Hwan Lee; Cheol Min Shin; Ji Hyun Park; Mi Kyoung Lee; Ryoung Hee Nam; Hee Eun Lee; Hye Seung Lee; Joo Sung Kim; Hyun Chae Jung; In Sung Song
Journal: Am J Physiol Gastrointest Liver Physiol Date: 2010-08-19 Impact factor: 4.052

Review 2. Oxidative stress involvement and gene expression in indomethacin-induced gastropathy.

Authors: Yuji Naito; Toshikazu Yoshikawa
Journal: Redox Rep Date: 2006 Impact factor: 4.412

3. Inhibition of both COX-1 and COX-2 is required for development of gastric damage in response to nonsteroidal antiinflammatory drugs.

Authors: A Tanaka; H Araki; Y Komoike; S Hase; K Takeuchi
Journal: J Physiol Paris Date: 2001 Jan-Dec

4. PTEN modulates vascular endothelial growth factor-mediated signaling and angiogenic effects.

Authors: Jianhua Huang; Christopher D Kontos
Journal: J Biol Chem Date: 2002-01-09 Impact factor: 5.157

5. Gastrointestinal toxicity with celecoxib vs nonsteroidal anti-inflammatory drugs for osteoarthritis and rheumatoid arthritis: the CLASS study: A randomized controlled trial. Celecoxib Long-term Arthritis Safety Study.

Authors: F E Silverstein; G Faich; J L Goldstein; L S Simon; T Pincus; A Whelton; R Makuch; G Eisen; N M Agrawal; W F Stenson; A M Burr; W W Zhao; J D Kent; J B Lefkowith; K M Verburg; G S Geis
Journal: JAMA Date: 2000-09-13 Impact factor: 56.272

6. Effects of growth factors and trefoil peptides on migration and replication in primary oxyntic cultures.

Authors: K Kato; M C Chen; M Nguyen; F S Lehmann; D K Podolsky; A H Soll
Journal: Am J Physiol Date: 1999-05

7. Cytoprotection by prostaglandins in rats. Prevention of gastric necrosis produced by alcohol, HCl, NaOH, hypertonic NaCl, and thermal injury.

Authors: A Robert; J E Nezamis; C Lancaster; A J Hanchar
Journal: Gastroenterology Date: 1979-09 Impact factor: 22.682

Mechanisms behind the increased vulnerability of the aging stomach to NSAID-related injury: perhaps not as simple as we may think.

1. Effect of aging on gastric mucosal defense mechanisms: ROS, apoptosis, angiogenesis, and sensory neurons.

Review 2. Oxidative stress involvement and gene expression in indomethacin-induced gastropathy.

3. Inhibition of both COX-1 and COX-2 is required for development of gastric damage in response to nonsteroidal antiinflammatory drugs.

4. PTEN modulates vascular endothelial growth factor-mediated signaling and angiogenic effects.

5. Gastrointestinal toxicity with celecoxib vs nonsteroidal anti-inflammatory drugs for osteoarthritis and rheumatoid arthritis: the CLASS study: A randomized controlled trial. Celecoxib Long-term Arthritis Safety Study.

6. Effects of growth factors and trefoil peptides on migration and replication in primary oxyntic cultures.

7. Cytoprotection by prostaglandins in rats. Prevention of gastric necrosis produced by alcohol, HCl, NaOH, hypertonic NaCl, and thermal injury.

8. Nonsteroidal anti-inflammatory drug use and increased risk for peptic ulcer disease in elderly persons.

9. Oral trefoil peptides protect against ethanol- and indomethacin-induced gastric injury in rats.

10. Peptic ulcerations are related to systemic rather than local effects of low-dose aspirin.

1. Increased vulnerability of the aging stomach to NSAIDs.

2. Clinical Risk Factors for Gastroduodenal Ulcer in Romanian Low-Dose Aspirin Consumers.