PURPOSE: Epidemiologic studies of the etiology of childhood obesity often use proxies for adiposity as outcomes. This study aimed to compare the ability of a range of proxy measures to detect associations with sedentary behavior. METHODS: Longitudinal study of children in the Gateshead Millennium Study who were 7 years at baseline and 9 years at follow-up. Associations between 2-year changes in objectively measured sedentary behavior and changes in proxies for adiposity (waist circumference, waist Z score, body mass index, body mass index Z score) and measurement of body composition (fat mass index from bioelectric impedance) were examined. Associations were tested with linear regression. RESULTS: Associations between 2-year increases in sedentary behavior and increases in adiposity were detectable by using the fat mass index as the outcome, but not the simple proxy measures of adiposity, as outcomes. CONCLUSIONS: Proxy measures are inferior to measures of body composition as outcomes in epidemiologic studies.
PURPOSE: Epidemiologic studies of the etiology of childhood obesity often use proxies for adiposity as outcomes. This study aimed to compare the ability of a range of proxy measures to detect associations with sedentary behavior. METHODS: Longitudinal study of children in the Gateshead Millennium Study who were 7 years at baseline and 9 years at follow-up. Associations between 2-year changes in objectively measured sedentary behavior and changes in proxies for adiposity (waist circumference, waist Z score, body mass index, body mass index Z score) and measurement of body composition (fat mass index from bioelectric impedance) were examined. Associations were tested with linear regression. RESULTS: Associations between 2-year increases in sedentary behavior and increases in adiposity were detectable by using the fat mass index as the outcome, but not the simple proxy measures of adiposity, as outcomes. CONCLUSIONS: Proxy measures are inferior to measures of body composition as outcomes in epidemiologic studies.
Authors: Paul J Collings; Soren Brage; Daniel D Bingham; Silvia Costa; Jane West; Rosemary R C McEachan; John Wright; Sally E Barber Journal: Med Sci Sports Exerc Date: 2017-05 Impact factor: 5.411
Authors: K D Mann; L D Howe; L Basterfield; K N Parkinson; M S Pearce; J K Reilly; A J Adamson; J J Reilly; X Janssen Journal: Int J Obes (Lond) Date: 2017-03-15 Impact factor: 5.095
Authors: Noel Po Tai Chan; Marie Tarrant; Esther Ngan; Hung Kwan So; Kris Yuet Wan Lok; Edmund Anthony Severn Nelson Journal: PLoS One Date: 2018-03-22 Impact factor: 3.240
Authors: Laura Basterfield; Jessica K Reilly; Mark S Pearce; Kathryn N Parkinson; Ashley J Adamson; John J Reilly; Stewart A Vella Journal: J Sci Med Sport Date: 2014-03-15 Impact factor: 4.319