OBJECTIVE: The aim of this study was to evaluate the need for antibiotic prescription in third molar surgery. STUDY DESIGN: A double-blind randomized study was carried out with 71 patients from CODONT (Dentistry Center of the Police of São Paulo). Amoxicillin, clindamycin, or no medication was administered for 7 days immediately after surgery. The participants evaluated the presence of pain, edema, interincisal distance (ID), presence of infection, Pell and Gregory classification, rescue analgesia, osteotomy, and odontosection. RESULTS: There was no difference (P < .05) between antibiotics and control over the surgery duration, dose, visual analog scale (VAS), ID, and edema, yet significant differences were seen over time for VAS, edema, and ID. CONCLUSIONS: Antibiotic prescription should not be indicated in all clinical conditions, yet it is necessary to correctly evaluate factors such as systemic condition of the patient, skill of the operator, and contamination of the surgical environment.
RCT Entities:
OBJECTIVE: The aim of this study was to evaluate the need for antibiotic prescription in third molar surgery. STUDY DESIGN: A double-blind randomized study was carried out with 71 patients from CODONT (Dentistry Center of the Police of São Paulo). Amoxicillin, clindamycin, or no medication was administered for 7 days immediately after surgery. The participants evaluated the presence of pain, edema, interincisal distance (ID), presence of infection, Pell and Gregory classification, rescue analgesia, osteotomy, and odontosection. RESULTS: There was no difference (P < .05) between antibiotics and control over the surgery duration, dose, visual analog scale (VAS), ID, and edema, yet significant differences were seen over time for VAS, edema, and ID. CONCLUSIONS: Antibiotic prescription should not be indicated in all clinical conditions, yet it is necessary to correctly evaluate factors such as systemic condition of the patient, skill of the operator, and contamination of the surgical environment.
Authors: Giovanni Lodi; Lorenzo Azzi; Elena Maria Varoni; Monica Pentenero; Massimo Del Fabbro; Antonio Carrassi; Andrea Sardella; Maddalena Manfredi Journal: Cochrane Database Syst Rev Date: 2021-02-24
Authors: Mario Alberto Isiordia-Espinoza; Othoniel H Aragon-Martinez; Ronell E Bollogna-Molina; Ángel J Alonso-Castro Journal: J Maxillofac Oral Surg Date: 2017-07-01
Authors: María-Iciar Arteagoitia; Eva Ramos; Gorka Santamaría; Julio Álvarez; Luis Barbier; Joseba Santamaría Journal: Med Oral Patol Oral Cir Bucal Date: 2016-01-01
Authors: Gabriele Cervino; Marco Cicciù; Antonio Biondi; Salvatore Bocchieri; Alan Scott Herford; Luigi Laino; Luca Fiorillo Journal: Antibiotics (Basel) Date: 2019-05-02