Literature DB >> 23082959

Biology of circulating nucleic acids and possible roles in diagnosis and treatment in diabetes and cancer.

Peter B Gahan1.   

Abstract

The presence of DNA and RNA circulating in human plasma and serum is described. The possible sources of the DNA/RNA in blood, their ability to enter other cells and to express in the recipient cells are discussed and the relationship with metastases considered. The possible role(s) of the DNA/RNA in clinical diagnosis, in monitoring treatment and in prognosis are considered for diabetes and oncology.

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Year:  2012        PMID： 23082959     DOI： 10.2174/187152612804142224

Source DB:  PubMed          Journal:  Infect Disord Drug Targets        ISSN： 1871-5265


  5 in total

Review 1.  Do circulating tumor cells, exosomes, and circulating tumor nucleic acids have clinical utility? A report of the association for molecular pathology.

Authors:  Bert Gold; Milena Cankovic; Larissa V Furtado; Frederick Meier; Christopher D Gocke
Journal:  J Mol Diagn       Date:  2015-05       Impact factor: 5.568

2.  Circulating cell-free DNA concentration and DNase I activity of peripheral blood plasma change in case of pregnancy with intrauterine growth restriction compared to normal pregnancy.

Authors:  Elizaveta Ershova; Vasilina Sergeeva; Maria Klimenko; Kristina Avetisova; Peter Klimenko; Edmund Kostyuk; Natalia Veiko; Roman Veiko; Vera Izevskaya; Sergey Kutsev; Svetlana Kostyuk
Journal:  Biomed Rep       Date:  2017-08-17

3.  The level of free circulating mitochondrial DNA in blood as predictor of death in case of acute coronary syndrome.

Authors:  Nikolay P Sudakov; Konstantin A Apartsin; Svetlana A Lepekhova; Sergey B Nikiforov; Alexander I Katyshev; Galina I Lifshits; Anna V Vybivantseva; Yuri M Konstantinov
Journal:  Eur J Med Res       Date:  2017-01-03       Impact factor: 2.175

4.  Circulating DNA in rheumatoid arthritis: pathological changes and association with clinically used serological markers.

Authors:  Elena Rykova; Aleksey Sizikov; Dirk Roggenbuck; Oksana Antonenko; Leonid Bryzgalov; Evgeniy Morozkin; Kseniya Skvortsova; Valentin Vlassov; Pavel Laktionov; Vladimir Kozlov
Journal:  Arthritis Res Ther       Date:  2017-05-02       Impact factor: 5.156

5.  Liquid Biopsy in Type 2 Diabetes Mellitus Management: Building Specific Biosignatures via Machine Learning.

Authors:  Makrina Karaglani; Maria Panagopoulou; Christina Cheimonidi; Ioannis Tsamardinos; Efstratios Maltezos; Nikolaos Papanas; Dimitrios Papazoglou; George Mastorakos; Ekaterini Chatzaki
Journal:  J Clin Med       Date:  2022-02-17       Impact factor: 4.241
  5 in total

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