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Literature DB >> 23081879

Divergent total synthesis of the antimitotic agent leiodermatolide.

Jens Willwacher¹, Nina Kausch-Busies, Alois Fürstner.

Abstract

Entities: Chemical

Mesh：

Substances：

Year: 2012 PMID： 23081879 DOI： 10.1002/anie.201206670

Source DB: PubMed Journal: Angew Chem Int Ed Engl ISSN： 1433-7851 Impact factor: 15.336

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11 in total

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Authors: O M Ogba; N C Warner; D J O'Leary; R H Grubbs
Journal: Chem Soc Rev Date: 2018-06-18 Impact factor: 54.564

2. Analogues of the Potent Antitumor Compound Leiodermatolide from a Deep-Water Sponge of the Genus Leiodermatium.

Authors: Amy E Wright; Jill C Roberts; Esther A Guzmán; Tara P Pitts; Shirley A Pomponi; John K Reed
Journal: J Nat Prod Date: 2017-01-30 Impact factor: 4.050

Review 3. Challenges and discoveries in the total synthesis of complex polyketide natural products.

Authors: Ian Paterson; Nelson Yuen Sum Lam
Journal: J Antibiot (Tokyo) Date: 2017-10-25 Impact factor: 2.649

4. Leiodermatolide, a novel marine natural product, has potent cytotoxic and antimitotic activity against cancer cells, appears to affect microtubule dynamics, and exhibits antitumor activity.

Authors: Esther A Guzmán; Qunli Xu; Tara P Pitts; Kaoru Ogawa Mitsuhashi; Cheryl Baker; Patricia A Linley; Judy Oestreicher; Karen Tendyke; Priscilla L Winder; Edward M Suh; Amy E Wright
Journal: Int J Cancer Date: 2016-07-19 Impact factor: 7.396

5. A Unified Approach to Polycyclic Alkaloids of the Ingenamine Estate: Total Syntheses of Keramaphidin B, Ingenamine, and Nominal Njaoamine I.

Authors: Zhanchao Meng; Simon M Spohr; Sandra Tobegen; Christophe Farès; Alois Fürstner
Journal: J Am Chem Soc Date: 2021-08-27 Impact factor: 15.419

6. Total synthesis and complete configurational assignment of amphirionin-2.

Authors: Shota Kato; Daichi Mizukami; Tomoya Sugai; Masashi Tsuda; Haruhiko Fuwa
Journal: Chem Sci Date: 2020-11-20 Impact factor: 9.825

7. Total Synthesis of Leiodermatolide A via Transfer Hydrogenative Allylation, Crotylation, and Propargylation: Polyketide Construction beyond Discrete Allyl- or Allenylmetal Reagents.

Authors: Yuk-Ming Siu; James Roane; Michael J Krische
Journal: J Am Chem Soc Date: 2021-07-08 Impact factor: 16.383