PURPOSE: To determine the utility of dual-energy perfusion CT (DEpCT) of non-diseased lung segments, using dual-source CT, in comparison with perfusion single-photon emission computed tomography (SPECT). MATERIALS AND METHODS: 28 patients (18 male and 10 female; mean age 63 years; age range 18-86 years) underwent DEpCT and SPECT within a 3-day interval. The presence and location of perfusion defects in each segment of the lungs were evaluated. RESULTS: Perfusion defects were noted in 7 of 361 segments (1.9%) by DEpCT and in 19 of 361 segments (5.3%) by perfusion SPECT. DEpCT was in good agreement with perfusion SPECT for 338 of 361 segments (93.6%). Intraobserver agreement was also good, ranging from 93.4 to 93.6% (κ = 0.64-0.75, p < 0.01). CONCLUSION: For non-diseased lung segments, DEpCT correlated well with SPECT.
PURPOSE: To determine the utility of dual-energy perfusion CT (DEpCT) of non-diseased lung segments, using dual-source CT, in comparison with perfusion single-photon emission computed tomography (SPECT). MATERIALS AND METHODS: 28 patients (18 male and 10 female; mean age 63 years; age range 18-86 years) underwent DEpCT and SPECT within a 3-day interval. The presence and location of perfusion defects in each segment of the lungs were evaluated. RESULTS: Perfusion defects were noted in 7 of 361 segments (1.9%) by DEpCT and in 19 of 361 segments (5.3%) by perfusion SPECT. DEpCT was in good agreement with perfusion SPECT for 338 of 361 segments (93.6%). Intraobserver agreement was also good, ranging from 93.4 to 93.6% (κ = 0.64-0.75, p < 0.01). CONCLUSION: For non-diseased lung segments, DEpCT correlated well with SPECT.
Authors: L B Marks; M T Munley; D P Spencer; G W Sherouse; G C Bentel; J Hoppenworth; M Chew; R J Jaszczak; R E Coleman; L R Prosnitz Journal: Int J Radiat Oncol Biol Phys Date: 1997-05-01 Impact factor: 7.038
Authors: Jan C Schenzle; Wieland H Sommer; Klement Neumaier; Gisela Michalski; Ursula Lechel; Konstantin Nikolaou; Christoph R Becker; Maximilian F Reiser; Thorsten R C Johnson Journal: Invest Radiol Date: 2010-06 Impact factor: 6.016
Authors: Sven F Thieme; Christoph R Becker; Marcus Hacker; Konstantin Nikolaou; Maximilian F Reiser; Thorsten R C Johnson Journal: Eur J Radiol Date: 2008-09-05 Impact factor: 3.528