Literature DB >> 23079718

A simple packed bed device for antibody labelled rare cell capture from whole blood.

Jason G Kralj1, Chandamany Arya, Alessandro Tona, Thomas P Forbes, Matthew S Munson, Lynn Sorbara, Sudhir Srivastava, Samuel P Forry.   

Abstract

We have developed a system to isolate rare cells from whole blood using commercially available components and simple microfluidics. We characterized the capture of MCF-7 cells spiked into whole human blood using this system to demonstrate that enrichment and enumeration studies give results similar to in situ surface-modified devices while reducing fabrication and operation complexity.

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Year:  2012        PMID: 23079718     DOI: 10.1039/c2lc41048f

Source DB:  PubMed          Journal:  Lab Chip        ISSN: 1473-0189            Impact factor:   6.799


  2 in total

Review 1.  Recent advances in microfluidic cell separations.

Authors:  Yan Gao; Wenjie Li; Dimitri Pappas
Journal:  Analyst       Date:  2013-06-19       Impact factor: 4.616

2.  A microfluidic column of water index-matched packed microspheres for label-free observation of water pollutants.

Authors:  Roberta Lanfranco; Janire Saez; Deborah Abati; Thomas Carzaniga; Fernando Benito-Lopez; Marco Buscaglia
Journal:  Mikrochim Acta       Date:  2021-03-28       Impact factor: 5.833

  2 in total

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