| Literature DB >> 23079653 |
Abstract
Deregulated energetics is a hallmark of malignancy, but metabolic heterogeneity among individual tumors is unknown. A study by Caro et al. in this issue of Cancer Cell demonstrates that a subset of lymphomas is defined by reliance on mitochondrial energy generation and is selectively killed when this pathway is impaired.Entities:
Year: 2012 PMID: 23079653 PMCID: PMC3495163 DOI: 10.1016/j.ccr.2012.09.023
Source DB: PubMed Journal: Cancer Cell ISSN: 1535-6108 Impact factor: 31.743