Literature DB >> 23079651

Cell cycle-based therapies move forward.

Marcos Malumbres1.   

Abstract

Targeted therapies directed against cell cycle regulators have been difficult to translate into the clinic. In this issue of Cancer Cell, Choi et al. and Sawai et al. rekindle the therapeutic value of inhibiting specific cyclin-dependent kinase complexes by demonstrating their requirements in the maintenance of breast tumors and leukemias.
Copyright © 2012 Elsevier Inc. All rights reserved.

Entities:  

Year:  2012        PMID： 23079651     DOI： 10.1016/j.ccr.2012.09.024

Source DB:  PubMed          Journal:  Cancer Cell        ISSN： 1535-6108            Impact factor:   31.743


  11 in total

Review 1.  Single-cell mass cytometry for analysis of immune system functional states.

Authors:  Zach B Bjornson; Garry P Nolan; Wendy J Fantl
Journal:  Curr Opin Immunol       Date:  2013-08-31       Impact factor: 7.486

2.  The identification of key genes in nasopharyngeal carcinoma by bioinformatics analysis of high-throughput data.

Authors:  Yanshan Ge; Zhengxi He; Yanqi Xiang; Dawei Wang; Yuping Yang; Jian Qiu; Yanhong Zhou
Journal:  Mol Biol Rep       Date:  2019-03-04       Impact factor: 2.316

3.  Bee venom protects against pancreatic cancer via inducing cell cycle arrest and apoptosis with suppression of cell migration.

Authors:  Jing Zhao; Weiguo Hu; Zejia Zhang; Zegao Zhou; Jiayue Duan; Zheng Dong; Hao Liu; Changqing Yan
Journal:  J Gastrointest Oncol       Date:  2022-04

4.  PD-0332991 induces G1 arrest of colorectal carcinoma cells through inhibition of the cyclin-dependent kinase-6 and retinoblastoma protein axis.

Authors:  Chunsheng Li; Ling Qi; Anita C Bellail; Chunhai Hao; Tongjun Liu
Journal:  Oncol Lett       Date:  2014-03-10       Impact factor: 2.967

5.  A Phase I study of cyclin-dependent kinase inhibitor, AT7519, in patients with advanced cancer: NCIC Clinical Trials Group IND 177.

Authors:  E X Chen; S Hotte; H Hirte; L L Siu; J Lyons; M Squires; S Lovell; S Turner; L McIntosh; L Seymour
Journal:  Br J Cancer       Date:  2014-11-13       Impact factor: 7.640

6.  Effects of metal ions on the structure and activity of a human anti-cyclin D1 single-chain variable fragment AD5.

Authors:  Ning Yang; Nannan Yao; Xiangzhi Liao; Xiaona Xie; Yan Wu; Chuanxi Fan; Jialiang Zhao; Guiying Li
Journal:  Mol Med Rep       Date:  2017-06-12       Impact factor: 2.952

7.  A kinase-independent function of CDK6 links the cell cycle to tumor angiogenesis.

Authors:  Karoline Kollmann; Gerwin Heller; Christine Schneckenleithner; Wolfgang Warsch; Ruth Scheicher; Rene G Ott; Markus Schäfer; Sabine Fajmann; Michaela Schlederer; Ana-Iris Schiefer; Ursula Reichart; Matthias Mayerhofer; Christoph Hoeller; Sabine Zöchbauer-Müller; Dontscho Kerjaschki; Christoph Bock; Lukas Kenner; Gerald Hoefler; Michael Freissmuth; Anthony R Green; Richard Moriggl; Meinrad Busslinger; Marcos Malumbres; Veronika Sexl
Journal:  Cancer Cell       Date:  2013-08-12       Impact factor: 31.743

8.  Quince peel polyphenolic extract blocks human colon adenocarcinoma LS174 cell growth and potentiates 5-fluorouracil efficacy.

Authors:  Ichrak Riahi-Chebbi; Meriam Haoues; Makram Essafi; Ons Zakraoui; Sami Fattouch; Habib Karoui; Khadija Essafi-Benkhadir
Journal:  Cancer Cell Int       Date:  2016-02-02       Impact factor: 5.722

9.  Meroterpenoids from the Brown Alga Cystoseira usneoides as Potential Anti-Inflammatory and Lung Anticancer Agents.

Authors:  Hanaa Zbakh; Eva Zubía; Carolina de Los Reyes; José M Calderón-Montaño; Miguel López-Lázaro; Virginia Motilva
Journal:  Mar Drugs       Date:  2020-04-11       Impact factor: 5.118

10.  Release from cell cycle arrest with Cdk4/6 inhibitors generates highly synchronized cell cycle progression in human cell culture.

Authors:  Eleanor Wendy Trotter; Iain Michael Hagan
Journal:  Open Biol       Date:  2020-10-14       Impact factor: 6.411
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