Literature DB >> 23077906

[Prognostic factors in breast cancer].

R Georgescu1, M F Coroş, Simona Stolnicu, Daniela Podeanu, S Sorlea, Anca Roşca, C Copotoiu.   

Abstract

UNLABELLED: Survival in breast cancer is determined by many factors, their influence is different. The aim of the study is to assess the impact on survival of various prognostic factors.
MATERIAL AND METHODS: We studied a total of 198 cases of histologically confirmed breast cancer patients, and we evaluated the impact of prognostic factors on survival.
RESULTS: The most important factor influencing survival is the preset of axillary metastasis(p: 0.0001). Other important prognostic factors are: tumor size (p: 0.003), tumor grading (p: 0.0025), N stage (p: 0.0001.) lymphovascular invasion (p 0.0005) and Nottingham Prognostic Index (p: 0.0109). The factors with no impact on survival were: histological type (p: 0.82), number of lymph nodes affected(p: 0.23), tumor necrosis(p: 0.49) and inflammatory infiltration (p: 0.2).
CONCLUSIONS: The most important prognostic factors are: axillary metastasis followed by tumor grading, NPI and lymphovascular invasion.

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Year:  2012        PMID: 23077906

Source DB:  PubMed          Journal:  Rev Med Chir Soc Med Nat Iasi        ISSN: 0048-7848


  3 in total

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Journal:  BMC Cancer       Date:  2015-04-14       Impact factor: 4.430

2.  High expression of Sonic Hedgehog signaling pathway genes indicates a risk of recurrence of breast carcinoma.

Authors:  Kuo-Shyang Jeng; I-Shyan Sheen; Wen-Juei Jeng; Ming-Che Yu; Hsin-I Hsiau; Fang-Yu Chang
Journal:  Onco Targets Ther       Date:  2013-12-27       Impact factor: 4.147

3.  Evaluation of the tracing effect of carbon nanoparticle and carbon nanoparticle-epirubicin suspension in axillary lymph node dissection for breast cancer treatment.

Authors:  Junze Du; Yongsong Zhang; Jia Ming; Jing Liu; Ling Zhong; Quankun Liang; Linjun Fan; Jun Jiang
Journal:  World J Surg Oncol       Date:  2016-06-22       Impact factor: 2.754

  3 in total

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