Literature DB >> 23077308

Tsg101 interacts with herpes simplex virus 1 VP1/2 and is a substrate of VP1/2 ubiquitin-specific protease domain activity.

Martina Caduco1, Alessandra Comin, Marta Toffoletto, Denis Munegato, Elena Sartori, Michele Celestino, Cristiano Salata, Cristina Parolin, Giorgio Palù, Arianna Calistri.   

Abstract

Ubiquitination/deubiquitination of key factors represent crucial steps in the biogenesis of multivesicular body (MVB) and sorting of transmembrane proteins. We and others previously demonstrated that MVB is involved in herpes simplex virus 1 (HSV-1) envelopment and budding. Here, we report that the HSV-1 large tegument protein, VP1/2, interacts with and regulates the ubiquitination of Tsg101, a cellular protein essential in MVB formation, thus identifying the first cellular substrate of a herpesviral deubiquitinating enzyme.

Entities:  

Mesh：

Substances：

Year:  2012        PMID： 23077308      PMCID： PMC3536428          DOI： 10.1128/JVI.01969-12

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  22 in total

1.  A null mutation in the UL36 gene of herpes simplex virus type 1 results in accumulation of unenveloped DNA-filled capsids in the cytoplasm of infected cells.

Authors:  P J Desai
Journal:  J Virol       Date:  2000-12       Impact factor: 5.103

2.  A single motif responsible for ubiquitin recognition and monoubiquitination in endocytic proteins.

Authors:  Simona Polo; Sara Sigismund; Mario Faretta; Monica Guidi; Maria Rosaria Capua; Giovanna Bossi; Hong Chen; Pietro De Camilli; Pier Paolo Di Fiore
Journal:  Nature       Date:  2002-03-28       Impact factor: 49.962

3.  AIP1/ALIX is a binding partner for HIV-1 p6 and EIAV p9 functioning in virus budding.

Authors:  Bettina Strack; Arianna Calistri; Stewart Craig; Elena Popova; Heinrich G Göttlinger
Journal:  Cell       Date:  2003-09-19       Impact factor: 41.582

4.  Tal, a Tsg101-specific E3 ubiquitin ligase, regulates receptor endocytosis and retrovirus budding.

Authors:  Ido Amit; Liat Yakir; Menachem Katz; Yaara Zwang; Mina D Marmor; Ami Citri; Keren Shtiegman; Iris Alroy; Shmuel Tuvia; Yuval Reiss; Eli Roubini; Maya Cohen; Ron Wides; Eran Bacharach; Ullrich Schubert; Yosef Yarden
Journal:  Genes Dev       Date:  2004-07-15       Impact factor: 11.361

5.  The pseudorabies virus VP1/2 tegument protein is required for intracellular capsid transport.

Authors:  G W Gant Luxton; Joy I-Hsuan Lee; Sarah Haverlock-Moyns; Joseph Martin Schober; Gregory Allan Smith
Journal:  J Virol       Date:  2006-01       Impact factor: 5.103

6.  Molecular genetics of herpes simplex virus. VI. Characterization of a temperature-sensitive mutant defective in the expression of all early viral gene products.

Authors:  D M Knipe; W Batterson; C Nosal; B Roizman; A Buchan
Journal:  J Virol       Date:  1981-05       Impact factor: 5.103

7.  A deubiquitinating enzyme encoded by HSV-1 belongs to a family of cysteine proteases that is conserved across the family Herpesviridae.

Authors:  Lisa M Kattenhorn; Gregory A Korbel; Benedikt M Kessler; Eric Spooner; Hidde L Ploegh
Journal:  Mol Cell       Date:  2005-08-19       Impact factor: 17.970

8.  Essential function of the pseudorabies virus UL36 gene product is independent of its interaction with the UL37 protein.

Authors:  Walter Fuchs; Barbara G Klupp; Harald Granzow; Thomas C Mettenleiter
Journal:  J Virol       Date:  2004-11       Impact factor: 5.103

9.  Mutagenesis of the active-site cysteine in the ubiquitin-specific protease contained in large tegument protein pUL36 of pseudorabies virus impairs viral replication in vitro and neuroinvasion in vivo.

Authors:  Sindy Böttcher; Christina Maresch; Harald Granzow; Barbara G Klupp; Jens P Teifke; Thomas C Mettenleiter
Journal:  J Virol       Date:  2008-04-09       Impact factor: 5.103

Review 10.  The complete DNA sequence of the long unique region in the genome of herpes simplex virus type 1.

Authors:  D J McGeoch; M A Dalrymple; A J Davison; A Dolan; M C Frame; D McNab; L J Perry; J E Scott; P Taylor
Journal:  J Gen Virol       Date:  1988-07       Impact factor: 3.891
View more
  2 in total

1.  Herpes Simplex Virus 1 Infection of Tree Shrews Differs from That of Mice in the Severity of Acute Infection and Viral Transcription in the Peripheral Nervous System.

Authors:  Lihong Li; Zhuoran Li; Erlin Wang; Rui Yang; Yu Xiao; Hongbo Han; Fengchao Lang; Xin Li; Yujie Xia; Feng Gao; Qihan Li; Nigel W Fraser; Jumin Zhou
Journal:  J Virol       Date:  2015-10-28       Impact factor: 5.103

2.  Recovery of an HMWP/hmwBP (pUL48/pUL47) complex from virions of human cytomegalovirus: subunit interactions, oligomer composition, and deubiquitylase activity.

Authors:  Jennifer A Tullman; Mary-Elizabeth Harmon; Michael Delannoy; Wade Gibson
Journal:  J Virol       Date:  2014-05-14       Impact factor: 5.103
  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.