Literature DB >> 23076650

Animal models of colorectal cancer.

Robert L Johnson1, James C Fleet.   

Abstract

Colorectal cancer is a heterogeneous disease that afflicts a large number of people in the USA. The use of animal models has the potential to increase our understanding of carcinogenesis, tumor biology, and the impact of specific molecular events on colon biology. In addition, animal models with features of specific human colorectal cancers can be used to test strategies for cancer prevention and treatment. In this review, we provide an overview of the mechanisms driving human cancer, we discuss the approaches one can take to model colon cancer in animals, and we describe a number of specific animal models that have been developed for the study of colon cancer. We believe that there are many valuable animal models to study various aspects of human colorectal cancer. However, opportunities for improving upon these models exist.

Entities:  

Mesh：

Year:  2013        PMID： 23076650      PMCID： PMC3572245          DOI： 10.1007/s10555-012-9404-6

Source DB:  PubMed          Journal:  Cancer Metastasis Rev        ISSN： 0167-7659            Impact factor:   9.264


  198 in total

1.  Dietary restriction during murine development provides protection against MNU-induced mutations.

Authors:  N Shima; R R Swiger; J A Heddle
Journal:  Mutat Res       Date:  2000-10-31       Impact factor: 2.433

2.  Germ-line mutations of the APC gene in 53 familial adenomatous polyposis patients.

Authors:  Y Miyoshi; H Ando; H Nagase; I Nishisho; A Horii; Y Miki; T Mori; J Utsunomiya; S Baba; G Petersen
Journal:  Proc Natl Acad Sci U S A       Date:  1992-05-15       Impact factor: 11.205

3.  Analysis of lung tumor initiation and progression using conditional expression of oncogenic K-ras.

Authors:  E L Jackson; N Willis; K Mercer; R T Bronson; D Crowley; R Montoya; T Jacks; D A Tuveson
Journal:  Genes Dev       Date:  2001-12-15       Impact factor: 11.361

4.  Induction of a beta-catenin-LEF-1 complex by wnt-1 and transforming mutants of beta-catenin.

Authors:  E Porfiri; B Rubinfeld; I Albert; K Hovanes; M Waterman; P Polakis
Journal:  Oncogene       Date:  1997-12-04       Impact factor: 9.867

5.  Mutant KRAS promotes hyperplasia and alters differentiation in the colon epithelium but does not expand the presumptive stem cell pool.

Authors:  Ying Feng; Guido T Bommer; Jenny Zhao; Maranne Green; Evan Sands; Yali Zhai; Kelly Brown; Aaron Burberry; Kathleen R Cho; Eric R Fearon
Journal:  Gastroenterology       Date:  2011-05-18       Impact factor: 22.682

6.  An Msh2 conditional knockout mouse for studying intestinal cancer and testing anticancer agents.

Authors:  Melanie H Kucherlapati; Kyeryoung Lee; Andrew A Nguyen; Alan B Clark; Harry Hou; Andrew Rosulek; Hua Li; Kan Yang; Kunhua Fan; Martin Lipkin; Roderick T Bronson; Linda Jelicks; Thomas A Kunkel; Raju Kucherlapati; Winfried Edelmann
Journal:  Gastroenterology       Date:  2009-11-18       Impact factor: 22.682

7.  BRAF mutation is frequently present in sporadic colorectal cancer with methylated hMLH1, but not in hereditary nonpolyposis colorectal cancer.

Authors:  Guoren Deng; Ian Bell; Suzanne Crawley; James Gum; Jonathan P Terdiman; Brian A Allen; Brindusa Truta; Marvin H Sleisenger; Young S Kim
Journal:  Clin Cancer Res       Date:  2004-01-01       Impact factor: 12.531

8.  Mutation and cancer: statistical study of retinoblastoma.

Authors:  A G Knudson
Journal:  Proc Natl Acad Sci U S A       Date:  1971-04       Impact factor: 11.205

9.  Feline gastrointestinal adenocarcinoma: a review and retrospective study.

Authors:  A E Cribb
Journal:  Can Vet J       Date:  1988-09       Impact factor: 1.008

10.  A knock-in mouse model reveals roles for nuclear Apc in cell proliferation, Wnt signal inhibition and tumor suppression.

Authors:  M Zeineldin; J Cunningham; W McGuinness; P Alltizer; B Cowley; B Blanchat; W Xu; D Pinson; K L Neufeld
Journal:  Oncogene       Date:  2011-09-26       Impact factor: 9.867
View more
  43 in total

Review 1.  Eicosanoid signaling in carcinogenesis of colorectal cancer.

Authors:  Yuxin Wang; Weicang Wang; Katherine Z Sanidad; Pei-An Shih; Xinfeng Zhao; Guodong Zhang
Journal:  Cancer Metastasis Rev       Date:  2018-09       Impact factor: 9.264

2.  A common antimicrobial additive increases colonic inflammation and colitis-associated colon tumorigenesis in mice.

Authors:  Haixia Yang; Weicang Wang; Kymberleigh A Romano; Min Gu; Katherine Z Sanidad; Daeyoung Kim; Jun Yang; Birgitta Schmidt; Dipak Panigrahy; Ruisong Pei; Derek A Martin; E Ilker Ozay; Yuxin Wang; Mingyue Song; Bradley W Bolling; Hang Xiao; Lisa M Minter; Guang-Yu Yang; Zhenhua Liu; Federico E Rey; Guodong Zhang
Journal:  Sci Transl Med       Date:  2018-05-30       Impact factor: 17.956

Review 3.  Multiple Roles of APC and its Therapeutic Implications in Colorectal Cancer.

Authors:  Lu Zhang; Jerry W Shay
Journal:  J Natl Cancer Inst       Date:  2017-08-01       Impact factor: 13.506

4.  Colon-specific tumorigenesis in mice driven by Cre-mediated inactivation of Apc and activation of mutant Kras.

Authors:  Alexander J Byun; Kenneth E Hung; James C Fleet; Roderick T Bronson; Joel B Mason; Paloma E Garcia; Jimmy W Crott
Journal:  Cancer Lett       Date:  2014-03-14       Impact factor: 8.679

5.  Sitagliptin, a dipeptidyl peptidase-4 inhibitor, suppresses CXCL5 and SDF-1 and does not accelerate intestinal neoplasia formation in ApcMin/+ mice fed a high-fat diet.

Authors:  Kaori Fujiwara; Takuya Inoue; Yujiro Henmi; Yoshimasa Hirata; Yutaka Naka; Azusa Hara; Kazuki Kakimoto; Sadaharu Nouda; Toshihiko Okada; Ken Kawakami; Toshihisa Takeuchi; Kazuhide Higuchi
Journal:  Oncol Lett       Date:  2017-08-01       Impact factor: 2.967

6.  A novel mouse model of sporadic colon cancer induced by combination of conditional Apc genes and chemical carcinogen in the absence of Cre recombinase.

Authors:  Jeffrey S Souris; Hannah J Zhang; Urszula Dougherty; Nai-Tzu Chen; Joseph V Waller; Leu-Wei Lo; John Hart; Chin-Tu Chen; Marc Bissonnette
Journal:  Carcinogenesis       Date:  2019-11-25       Impact factor: 4.944

7.  Generation of an inducible colon-specific Cre enzyme mouse line for colon cancer research.

Authors:  Paul W Tetteh; Kai Kretzschmar; Harry Begthel; Maaike van den Born; Jeroen Korving; Folkert Morsink; Henner Farin; Johan H van Es; G Johan A Offerhaus; Hans Clevers
Journal:  Proc Natl Acad Sci U S A       Date:  2016-10-05       Impact factor: 11.205

8.  In Vitro Models of the Small Intestine: Engineering Challenges and Engineering Solutions.

Authors:  Sarah A Hewes; Reid L Wilson; Mary K Estes; Noah F Shroyer; Sarah E Blutt; K Jane Grande-Allen
Journal:  Tissue Eng Part B Rev       Date:  2020-03-23       Impact factor: 6.389

Review 9.  Development of Preclinical Models to Understand and Treat Colorectal Cancer.

Authors:  Judith S Sebolt-Leopold
Journal:  Clin Colon Rectal Surg       Date:  2018-04-01

10.  Role of neutral ceramidase in colon cancer.

Authors:  Mónica García-Barros; Nicolas Coant; Toshihiko Kawamori; Masayuki Wada; Ashley J Snider; Jean-Philip Truman; Bill X Wu; Hideki Furuya; Christopher J Clarke; Agnieszka B Bialkowska; Amr Ghaleb; Vincent W Yang; Lina M Obeid; Yusuf A Hannun
Journal:  FASEB J       Date:  2016-09-08       Impact factor: 5.191
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.