Literature DB >> 23076406

Pathophysiology of the aging kidney and therapeutic interventions.

Keizo Kanasaki1, Munehiro Kitada, Daisuke Koya.   

Abstract

Kidneys are among the organs affected by the aging process. Aging kidneys are characterized by progressive scarring and measurable declines in renal function. Deficiencies in renal function are associated with mortality in all populations. Therefore, if the kidneys age at an accelerated rate relative to the other organs in a particular individual, then slowing or reversing the kidney aging process may be a therapeutically useful strategy. In this review, we will discuss the physiology and pathogenesis of kidney aging and analyze potential therapeutic strategies for halting the aging process in the kidneys.

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Year:  2012        PMID： 23076406     DOI： 10.1038/hr.2012.159

Source DB:  PubMed          Journal:  Hypertens Res        ISSN： 0916-9636            Impact factor:   3.872


  16 in total

Review 1.  The biological significance of angiotensin-converting enzyme inhibition to combat kidney fibrosis.

Authors:  Takako Nagai; Kyoko Nitta; Megumi Kanasaki; Daisuke Koya; Keizo Kanasaki
Journal:  Clin Exp Nephrol       Date:  2014-07-01       Impact factor: 2.801

2.  A dual agonist of farnesoid X receptor (FXR) and the G protein-coupled receptor TGR5, INT-767, reverses age-related kidney disease in mice.

Authors:  Xiaoxin X Wang; Yuhuan Luo; Dong Wang; Luciano Adorini; Mark Pruzanski; Evgenia Dobrinskikh; Moshe Levi
Journal:  J Biol Chem       Date:  2017-06-08       Impact factor: 5.157

Review 3.  Hip fractures in a geriatric population - rehabilitation based on patients needs.

Authors:  Natasa Radosavljevic; Dejan Nikolic; Milica Lazovic; Aleksandar Jeremic
Journal:  Aging Dis       Date:  2014-06-01       Impact factor: 6.745

4.  Does Age Matter? Association Between Usual Source of Care and Hypertension Control in the US Population: Data From NHANES 2007-2012.

Authors:  John M Dinkler; Catherine A Sugar; José J Escarce; Michael K Ong; Carol M Mangione
Journal:  Am J Hypertens       Date:  2016-02-16       Impact factor: 2.689

5.  Genetic Background and Clinicopathologic Features of Adult-onset Nephronophthisis.

Authors:  Takuya Fujimaru; Kunio Kawanishi; Takayasu Mori; Eikan Mishima; Akinari Sekine; Motoko Chiga; Masayuki Mizui; Noriaki Sato; Motoko Yanagita; Yuki Ooki; Kiyotaka Nagahama; Yuko Ohnuki; Naoto Hamano; Saki Watanabe; Toshio Mochizuki; Katsushi Nagatsuji; Kenichi Tanaka; Tatsuo Tsukamoto; Hideo Tsushima; Mamiko Shimamoto; Takahiro Tsuji; Tamaki Kuyama; Shinya Kawamoto; Kenji Maki; Ai Katsuma; Mariko Oishi; Kouhei Yamamoto; Shintaro Mandai; Hiroaki Kikuchi; Fumiaki Ando; Yutaro Mori; Koichiro Susa; Soichiro Iimori; Shotaro Naito; Tatemitsu Rai; Junichi Hoshino; Yoshifumi Ubara; Mariko Miyazaki; Michio Nagata; Shinichi Uchida; Eisei Sohara
Journal:  Kidney Int Rep       Date:  2021-03-04

6.  The effect of renal cortical thickness on the treatment outcomes of kidney stones treated with shockwave lithotripsy.

Authors:  Chi-Fai Ng; Sylvia Luke; Peter K F Chiu; Jeremy Y C Teoh; Ka-Tak Wong; Simon S M Hou
Journal:  Korean J Urol       Date:  2015-04-28

Review 7.  N-acetyl-seryl-aspartyl-lysyl-proline: a valuable endogenous anti-fibrotic peptide for combating kidney fibrosis in diabetes.

Authors:  Keizo Kanasaki; Takako Nagai; Kyoko Nitta; Munehiro Kitada; Daisuke Koya
Journal:  Front Pharmacol       Date:  2014-04-14       Impact factor: 5.810

8.  Oral Administration of N-Acetyl-seryl-aspartyl-lysyl-proline Ameliorates Kidney Disease in Both Type 1 and Type 2 Diabetic Mice via a Therapeutic Regimen.

Authors:  Kyoko Nitta; Sen Shi; Takako Nagai; Megumi Kanasaki; Munehiro Kitada; Swayam Prakash Srivastava; Masakazu Haneda; Keizo Kanasaki; Daisuke Koya
Journal:  Biomed Res Int       Date:  2016-03-20       Impact factor: 3.411

Review 9.  The role of renal dipeptidyl peptidase-4 in kidney disease: renal effects of dipeptidyl peptidase-4 inhibitors with a focus on linagliptin.

Authors:  Keizo Kanasaki
Journal:  Clin Sci (Lond)       Date:  2018-02-28       Impact factor: 6.124

Review 10.  The Role of Ageing and Parenchymal Senescence on Macrophage Function and Fibrosis.

Authors:  Ross A Campbell; Marie-Helena Docherty; David A Ferenbach; Katie J Mylonas
Journal:  Front Immunol       Date:  2021-06-17       Impact factor: 7.561
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