Literature DB >> 2307620

FR109615, a new antifungal antibiotic from Streptomyces setonii. Taxonomy, fermentation, isolation, physico-chemical properties and biological activity.

T Iwamoto1, E Tsujii, M Ezaki, A Fujie, S Hashimoto, M Okuhara, M Kohsaka, H Imanaka, K Kawabata, Y Inamoto.   

Abstract

FR109615, a new antibiotic active against Candida, was isolated from Streptomyces setonii No. 7562. Based on the spectroscopic data, the structure of FR109615 was elucidated as cis-2-aminocyclopentane-1-carboxylic acid (1). The compound showed the excellent in vivo efficacy in a generalized infection test of mice.

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Year:  1990        PMID： 2307620     DOI： 10.7164/antibiotics.43.1

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN： 0021-8820            Impact factor:   2.649


  10 in total

1.  In vitro activity and in vivo efficacy of icofungipen (PLD-118), a novel oral antifungal agent, against the pathogenic yeast Candida albicans.

Authors:  Andreja Hasenoehrl; Tatjana Galic; Gabrijela Ergovic; Natasa Marsic; Mihael Skerlev; Joachim Mittendorf; Ulrich Geschke; Axel Schmidt; Wolfgang Schoenfeld
Journal:  Antimicrob Agents Chemother       Date:  2006-09       Impact factor: 5.191

2.  Molecular mode of action of the antifungal beta-amino acid BAY 10-8888.

Authors:  K Ziegelbauer; P Babczinski; W Schönfeld
Journal:  Antimicrob Agents Chemother       Date:  1998-09       Impact factor: 5.191

3.  Synthesis, characterization and computational study on potential inhibitory action of novel azo imidazole derivatives against COVID-19 main protease (Mpro: 6LU7).

Authors:  Abhijit Chhetri; Sailesh Chettri; Pranesh Rai; Dipu Kumar Mishra; Biswajit Sinha; Dhiraj Brahman
Journal:  J Mol Struct       Date:  2020-09-18       Impact factor: 3.196

4.  Discovery of a new antifungal agent ASP2397 using a silkworm model of Aspergillus fumigatus infection.

Authors:  Ikuko Nakamura; Ryuichi Kanasaki; Koji Yoshikawa; Shigetada Furukawa; Akihiko Fujie; Hiroshi Hamamoto; Kazuhisa Sekimizu
Journal:  J Antibiot (Tokyo)       Date:  2016-08-31       Impact factor: 2.649

Review 5.  The Mechanistic Targets of Antifungal Agents: An Overview.

Authors:  Tryphon K Mazu; Barbara A Bricker; Hernan Flores-Rozas; Seth Y Ablordeppey
Journal:  Mini Rev Med Chem       Date:  2016       Impact factor: 3.862

6.  Decreased accumulation or increased isoleucyl-tRNA synthetase activity confers resistance to the cyclic beta-amino acid BAY 10-8888 in Candida albicans and Candida tropicalis.

Authors:  K Ziegelbauer
Journal:  Antimicrob Agents Chemother       Date:  1998-07       Impact factor: 5.191

Review 7.  Amino Acid Based Antimicrobial Agents - Synthesis and Properties.

Authors:  Michał G Nowak; Andrzej S Skwarecki; Maria J Milewska
Journal:  ChemMedChem       Date:  2021-10-01       Impact factor: 3.540

8.  Littoral lichens as a novel source of potentially bioactive Actinobacteria.

Authors:  Delphine Parrot; Sanjay Antony-Babu; Laurent Intertaglia; Martin Grube; Sophie Tomasi; Marcelino T Suzuki
Journal:  Sci Rep       Date:  2015-10-30       Impact factor: 4.379

9.  New Morphiceptin Peptidomimetic Incorporating (1S,2R,3S,4S,5R)-2-Amino-3,4,5-trihydroxycyclopen-tane-1-carboxylic acid: Synthesis and Structural Study.

Authors:  Raquel Soengas; Marcos Lorca; Begoña Pampín; Víctor M Sánchez-Pedregal; Ramón J Estévez; Juan C Estévez
Journal:  Molecules       Date:  2020-06-01       Impact factor: 4.411

10.  iChip-Inspired Isolation, Bioactivities and Dereplication of Actinomycetota from Portuguese Beach Sediments.

Authors:  José Diogo Neves Dos Santos; Susana Afonso João; Jesús Martín; Francisca Vicente; Fernando Reyes; Olga Maria Lage
Journal:  Microorganisms       Date:  2022-07-20
  10 in total

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