Tatjana Novakovic-Agopian1, Anthony J-W Chen, Scott Rome, Annemarie Rossi, Gary Abrams, Mark DʼEsposito, Gary Turner, Ryan McKim, Jim Muir, Nancy Hills, Cathy Kennedy, John Garfinkle, Michelle Murphy, Deborah Binder, Holli Castelli. 1. Veteran's Administration Medical Center, San Francisco (Drs Novakovic-Agopian, Chen, Abrams, McKim, and Murphy and Mss Rossi and Binder); Veteran's Administration Northern California Health Care System, Martinez (Drs Novakovic-Agopian, Chen, D'Esposito, and Muir and Ms Binder); California Pacific Regional Rehabilitation Center, San Francisco (Drs Novakovic-Agopian and Rome; Mss Rossi, Kennedy, and Castelli; and Mr Garfinkle), University of California, San Francisco (Drs Novakovic-Agopian, Chen, Abrams, and Hills); University of California, Berkeley (Drs Chen and D'Esposito), California; and Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada (Dr Turner).
Abstract
OBJECTIVES: To validate a new functional assessment tool, the Goal Processing Scale (GPS), and to apply it for testing for sources of dysfunction in patients with acquired brain injury. Determining which component processes of executive functioning underlie poor performance in complex, low-structure settings would be valuable for the assessment of deficits and for evaluating the effectiveness of treatments. PARTICIPANTS: Nineteen individuals with chronic acquired brain injury (mean age = 41.4 years; chronicity: 6 months to 39 years). MAIN MEASURES: Two functional assessment tasks: (1) GPS, which evaluates functional performance in the context of achieving a goal in a "real-world" setting, with rating scales measuring overall performance and 8 subdomains of executive functioning; (2) Multiple Errands Test, an unstructured assessment of ability to adhere to rules and complete multiple "real-world" tasks in a short time; and (3) a neuropsychological battery. RESULTS: Intraclass correlation coefficients for 2 independent raters ranged from 0.75 to 0.98 for the GPS overall composite score and the subdomain scores. Performance on GPS overall and several subdomain scores correlated with performance on the Multiple Errands Test. Working memory and learning/memory neuropsychological measures predicted functional performance as measured using the GPS. DISCUSSION: The GPS shows high interrater reliability, suggesting convergent validity with an established functional performance measure, and produces useful information regarding strengths and weaknesses in different subdomains of executive functioning. Working memory and learning/memory appear to be key determinants of goal-directed functioning for these individuals with brain injury.
OBJECTIVES: To validate a new functional assessment tool, the Goal Processing Scale (GPS), and to apply it for testing for sources of dysfunction in patients with acquired brain injury. Determining which component processes of executive functioning underlie poor performance in complex, low-structure settings would be valuable for the assessment of deficits and for evaluating the effectiveness of treatments. PARTICIPANTS: Nineteen individuals with chronic acquired brain injury (mean age = 41.4 years; chronicity: 6 months to 39 years). MAIN MEASURES: Two functional assessment tasks: (1) GPS, which evaluates functional performance in the context of achieving a goal in a "real-world" setting, with rating scales measuring overall performance and 8 subdomains of executive functioning; (2) Multiple Errands Test, an unstructured assessment of ability to adhere to rules and complete multiple "real-world" tasks in a short time; and (3) a neuropsychological battery. RESULTS: Intraclass correlation coefficients for 2 independent raters ranged from 0.75 to 0.98 for the GPS overall composite score and the subdomain scores. Performance on GPS overall and several subdomain scores correlated with performance on the Multiple Errands Test. Working memory and learning/memory neuropsychological measures predicted functional performance as measured using the GPS. DISCUSSION: The GPS shows high interrater reliability, suggesting convergent validity with an established functional performance measure, and produces useful information regarding strengths and weaknesses in different subdomains of executive functioning. Working memory and learning/memory appear to be key determinants of goal-directed functioning for these individuals with brain injury.
Authors: Tatjana Novakovic-Agopian; Erica Kornblith; Gary Abrams; Joaquin Burciaga-Rosales; Fred Loya; Mark D'Esposito; Anthony J W Chen Journal: J Neurotrauma Date: 2018-07-23 Impact factor: 5.269