Literature DB >> 23074554

No more milk in milk-alkali syndrome: a case report.

Ali Almusawi1, Shurooq Alhawaj, Mohammed Al-Mousawi, Tareq Dashti.   

Abstract

This is a case of Milk-AlKali syndrome in a patient who presented with the classical triad of hypercalcemia, metabolic alkalosis and renal impairment. The source of calcium was over-the-counter calcium-containing antacid (Tums®). Milk-alkali syndrome was first recognized secondary to treatment of peptic ulcer disease with milk and absorbable alkali. Its incidence fell after the introduction of H2-blocker and proton pump inhibitor. However, it is one of the leading causes of hypercalcemia nowadays because of the wide availability, increased marketing and use of calcium carbonate especially in osteoporosis prevention and treatment. The demographics of milk-alkali syndrome have changed compared to when it was initially described. The presentation could be acute, subacute or chronic. Early diagnosis, discounting calcium supplement and intravenous hydration are the mainstay of MAS management.

Entities:  

Keywords:  Calcium-alkali syndrome; Hypercalcemia; MAS; Milk-alkali syndrome

Year:  2012        PMID: 23074554      PMCID: PMC3472573          DOI: 10.5001/omj.2012.101

Source DB:  PubMed          Journal:  Oman Med J        ISSN: 1999-768X


  10 in total

1.  Milk alkali syndrome without the milk.

Authors:  Michail Kaklamanos; Petros Perros
Journal:  BMJ       Date:  2007-08-25

2.  Landmark article May 15, 1915: Gastric and duodenal ulcer. Medical cure by an efficient removal of gastric juice corrosion. By Bertram W. Sippy.

Authors:  B W Sippy
Journal:  JAMA       Date:  1983-10-28       Impact factor: 56.272

3.  Hypercalcaemia and metabolic alkalosis with betel nut chewing: emphasis on its integrative pathophysiology.

Authors:  Shih-Hua Lin; Yuh-Feng Lin; Surinder Cheema-Dhadli; Mogamat Razeen Davids; Mitchell L Halperin
Journal:  Nephrol Dial Transplant       Date:  2002-05       Impact factor: 5.992

Review 4.  Milk-alkali syndrome: a historical review and description of the modern version of the syndrome.

Authors:  Douglas P Beall; Heidi B Henslee; Heather R Webb; R Hal Scofield
Journal:  Am J Med Sci       Date:  2006-05       Impact factor: 2.378

5.  Milk-alkali syndrome is a major cause of hypercalcaemia among non-end-stage renal disease (non-ESRD) inpatients.

Authors:  Michalis K Picolos; Victor R Lavis; Philip R Orlander
Journal:  Clin Endocrinol (Oxf)       Date:  2005-11       Impact factor: 3.478

6.  The milk-alkali syndrome caused by betelnuts in oyster shell paste.

Authors:  K D Wu; R B Chuang; F L Wu; W A Hsu; I S Jan; K S Tsai
Journal:  J Toxicol Clin Toxicol       Date:  1996

7.  Got calcium? Welcome to the calcium-alkali syndrome.

Authors:  Ami M Patel; Stanley Goldfarb
Journal:  J Am Soc Nephrol       Date:  2010-04-22       Impact factor: 10.121

8.  Milk-alkali syndrome associated with calcium carbonate consumption. Report of 7 patients with parathyroid hormone levels and an estimate of prevalence among patients hospitalized with hypercalcemia.

Authors:  D P Beall; R H Scofield
Journal:  Medicine (Baltimore)       Date:  1995-03       Impact factor: 1.889

Review 9.  Milk-alkali syndrome.

Authors:  Boris I Medarov
Journal:  Mayo Clin Proc       Date:  2009-03       Impact factor: 7.616

10.  Milk alkali syndrome.

Authors:  B McGuinness; J I Logan
Journal:  Ulster Med J       Date:  2002-11
  10 in total

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