Literature DB >> 23073186

Solid state grinding as a tool to aid enantiomeric resolution by cocrystallisation.

Mark D Eddleston1, Mihails Arhangelskis, Tomislav Friščić, William Jones.   

Abstract

The formation of diastereomeric cocrystals of malic acid and tartaric acid was investigated by liquid-assisted grinding in the solid state. We demonstrate that racemic malic acid can be converted into two distinct diastereomeric cocrystal phases by grinding with a single enantiomer of tartaric acid.

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Year:  2012        PMID： 23073186     DOI： 10.1039/c2cc36130b

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  2 in total

Review 1.  Mechanochemistry: A Green Approach in the Preparation of Pharmaceutical Cocrystals.

Authors:  Mizraín Solares-Briones; Guadalupe Coyote-Dotor; José C Páez-Franco; Miriam R Zermeño-Ortega; Carmen Myriam de la O Contreras; Daniel Canseco-González; Alcives Avila-Sorrosa; David Morales-Morales; Juan M Germán-Acacio
Journal:  Pharmaceutics       Date:  2021-05-25       Impact factor: 6.321

Review 2.  Mechanochemistry of nucleosides, nucleotides and related materials.

Authors:  Olga Eguaogie; Joseph S Vyle; Patrick F Conlon; Manuela A Gîlea; Yipei Liang
Journal:  Beilstein J Org Chem       Date:  2018-04-27       Impact factor: 2.883
  2 in total

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