Literature DB >> 23072903

How does high-fat diet induce adipose tissue fibrosis?

Jeffrey E Pessin1, Hyokjoon Kwon.   

Abstract

Obesity is one of the most serious pandemic health problems in modern society and the predisposing factor for the type 2 diabetes mellitus. Chronic low-grade inflammation mediates the pathogenesis of insulin resistance in obese humans and rodents, and white adipose tissue is one of major tissues to modulate inflammation. Obese humans and rodents show dynamic changes of immunocellular compositions in white adipose tissue to induce inflammatory responses. Innate and adaptive immune responses mainly mediated by macrophages and T cells contribute insulin resistance. Recently, it has been shown that adipose tissue fibrosis is also enhanced in obese humans and rodents along with inflammatory responses, and suppression of adipose tissue fibrosis shows improved insulin sensitivity in rodent models, suggesting that adipose tissue fibrosis is involved in insulin resistance.

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Year:  2012        PMID： 23072903      PMCID： PMC3654516          DOI： 10.2310/JIM.0b013e318271fdb9

Source DB:  PubMed          Journal:  J Investig Med        ISSN： 1081-5589            Impact factor:   2.895


  45 in total

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Journal:  Proc Natl Acad Sci U S A       Date:  1993-04-15       Impact factor: 11.205

8.  IRS-1-mediated inhibition of insulin receptor tyrosine kinase activity in TNF-alpha- and obesity-induced insulin resistance.

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Journal:  Science       Date:  1996-02-02       Impact factor: 47.728

9.  Molecular mechanisms of antifibrotic effect of interferon gamma in bleomycin-mouse model of lung fibrosis: downregulation of TGF-beta and procollagen I and III gene expression.

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Journal:  Exp Lung Res       Date:  1995 Sep-Oct       Impact factor: 2.459

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Authors:  G S Hotamisligil; N S Shargill; B M Spiegelman
Journal:  Science       Date:  1993-01-01       Impact factor: 47.728
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  10 in total

1.  Profibrotic Infrapatellar Fat Pad Remodeling Without M1 Macrophage Polarization Precedes Knee Osteoarthritis in Mice With Diet-Induced Obesity.

Authors:  Erika Barboza; Joanna Hudson; Wan-Pin Chang; Susan Kovats; Rheal A Towner; Robert Silasi-Mansat; Florea Lupu; Collin Kent; Timothy M Griffin
Journal:  Arthritis Rheumatol       Date:  2017-04-28       Impact factor: 10.995

2.  The Association Between Subcutaneous Fat Density and the Propensity to Store Fat Viscerally.

Authors:  Aaron J Yeoh; Alison Pedley; Klara J Rosenquist; Udo Hoffmann; Caroline S Fox
Journal:  J Clin Endocrinol Metab       Date:  2015-06-10       Impact factor: 5.958

3.  Increased fibrosis: A novel means by which GH influences white adipose tissue function.

Authors:  Lara A Householder; Ross Comisford; Silvana Duran-Ortiz; Kevin Lee; Katie Troike; Cody Wilson; Adam Jara; Mitchell Harberson; Edward O List; John J Kopchick; Darlene E Berryman
Journal:  Growth Horm IGF Res       Date:  2017-12-20       Impact factor: 2.372

4.  A High-Fat Diet Promotes Mammary Gland Myofibroblast Differentiation through MicroRNA 140 Downregulation.

Authors:  Benjamin Wolfson; Yongshu Zhang; Ramkishore Gernapudi; Nadire Duru; Yuan Yao; Pang-Kuo Lo; Qun Zhou
Journal:  Mol Cell Biol       Date:  2017-02-01       Impact factor: 4.272

5.  Adipose tissue fibrosis.

Authors:  Christa Buechler; Sabrina Krautbauer; Kristina Eisinger
Journal:  World J Diabetes       Date:  2015-05-15

6.  Adipocyte hypertrophy, inflammation and fibrosis characterize subcutaneous adipose tissue of healthy, non-obese subjects predisposed to type 2 diabetes.

Authors:  A M Josefin Henninger; Björn Eliasson; Lachmi E Jenndahl; Ann Hammarstedt
Journal:  PLoS One       Date:  2014-08-22       Impact factor: 3.240

Review 7.  Obesity: An Immunometabolic Perspective.

Authors:  Indrani Ray; Sushil K Mahata; Rajat K De
Journal:  Front Endocrinol (Lausanne)       Date:  2016-12-12       Impact factor: 5.555

8.  Effects of detraining and retraining on muscle energy-sensing network and meteorin-like levels in obese mice.

Authors:  Ju Yong Bae; Jinhee Woo; Sunghwun Kang; Ki Ok Shin
Journal:  Lipids Health Dis       Date:  2018-04-27       Impact factor: 3.876

Review 9.  Obesity and the Development of Lung Fibrosis.

Authors:  Xia Guo; Christudas Sunil; Guoqing Qian
Journal:  Front Pharmacol       Date:  2022-01-10       Impact factor: 5.810

Review 10.  Adipose tissue immune response: novel triggers and consequences for chronic inflammatory conditions.

Authors:  Giorgio Ghigliotti; Chiara Barisione; Silvano Garibaldi; Patrizia Fabbi; Claudio Brunelli; Paolo Spallarossa; Paola Altieri; Gianmarco Rosa; Giovanni Spinella; Domenico Palombo; Razvan Arsenescu; Violeta Arsenescu
Journal:  Inflammation       Date:  2014-08       Impact factor: 4.092
  10 in total

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