Literature DB >> 23070721

Secondary infertility due to use of low-dose finasteride.

Ahmet Şalvarci1, Okan Istanbulluoğlu.   

Abstract

Herein, we present an unusual case of secondary infertility after prolonged use of low-dose finasteride for androgenetic alopecia in a 40-year-old man. We detected sperm DNA damage in the patient. Despite such a long-term use, we observed that impairment in semen parameters and sperm DNA fragmentation index regressed after the drug was discontinued. Consequently, pregnancy occurred and resulted in live birth.

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Year:  2012        PMID： 23070721     DOI： 10.1007/s11255-012-0315-9

Source DB:  PubMed          Journal:  Int Urol Nephrol        ISSN： 0301-1623            Impact factor:   2.370


  9 in total

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Authors:  J W Overstreet; V L Fuh; J Gould; S S Howards; M M Lieber; W Hellstrom; S Shapiro; P Carroll; R S Corfman; S Petrou; R Lewis; P Toth; T Shown; J Roy; J P Jarow; J Bonilla; C A Jacobsen; D Z Wang; K D Kaufman
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Review 5.  Therapeutic hotline. Treatment of androgenic alopecia with finasteride may result in a high grade prostate cancer in patients: fact or fiction?

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7.  Finasteride-induced secondary infertility associated with sperm DNA damage.

Authors:  Hin Yu Vincent Tu; Armand Zini
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8.  Claudin-11 expression and localisation is regulated by androgens in rat Sertoli cells in vitro.

Authors:  Tu'uhevaha J Kaitu'u-Lino; Pavel Sluka; Caroline F H Foo; Peter G Stanton
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  9 in total
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Review 2.  Safety Profile of Finasteride: Distribution of Adverse Effects According to Structural and Informational Dichotomies of the Mind/Brain.

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Review 4.  Male fertility and skin diseases.

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Review 5.  Secondary infertility and the aging male, overview.

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6.  Connexin 43 expression in the testes during postnatal development of finasteride-treated male rat offspring.

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  6 in total

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