| Literature DB >> 2307065 |
Abstract
A revised model of DNA packaging into chromosomes is presented. Its features are consistent with observed structural dimensions and the molecular periodicities related to transcription, replication and matrix attachment domains. The transitions between euchromatic, heterochromatic and metaphase states are explained simply. Molecular and physical properties of chromosomal bands, and their correlation with specific DNA sequence motifs are discussed.Mesh:
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Year: 1990 PMID: 2307065 DOI: 10.1002/cyto.990110104
Source DB: PubMed Journal: Cytometry ISSN: 0196-4763