| Literature DB >> 230702 |
G Pettersson, H Ahlman, A Dahlström, J Kewenter, I Larsson, P A Larsson.
Abstract
The effect of transmural field stimulation (TFS)--in vitro--on the sertonin (5-HT) content in enterochromafffin cells (EC) in rat duodenum was studied with a cytofluorimetric method. TFS caused a significant 25% decrease of 5-HT in EC. The presence of tetrodotoxin or d,1-propranolol in the stimulation bath antagonized the effect of TFS. In biopsies from rats pretreated with 6-OH-dopamine TFS had no effect of the 5-HT content in EC. The results of the present study strongly suggest, that the TFS induced decrease in 5-HT content is due to a direct neural, probably beta-adrenoceptor mediated, influence on the EC.Entities:
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Year: 1979 PMID： 230702 DOI： 10.1111/j.1748-1716.1979.tb06445.x
Source DB: PubMed Journal: Acta Physiol Scand ISSN： 0001-6772