Literature DB >> 23067231

Copper(I)-catalyzed intramolecular O-arylation for the synthesis of 2,3,4,9-tetrahydro-1H-xanthen-1-ones with low loads of CuCl.

Kavitha Sudheendran1, Chandi C Malakar, Jürgen Conrad, Uwe Beifuss.   

Abstract

As little as 0.5 mol % CuCl is sufficient to catalyze the intramolecular O-arylation of easily accessible 2-(2-bromobenzyl)cyclohexane-1,3-diones to provide the corresponding 2,3,4,9-tetrahydro-1H-xanthen-1-ones with yields ranging from 83% to 99%.

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Year:  2012        PMID: 23067231     DOI: 10.1021/jo3018318

Source DB:  PubMed          Journal:  J Org Chem        ISSN: 0022-3263            Impact factor:   4.354


  1 in total

1.  Crystal structure of 3-hy-droxy-2-(4-hy-droxy-3-meth-oxy-phenyl-methyl)-5,5-di-methyl-cyclo-hex-2-enone.

Authors:  Agnese Stikute; Karina Skestere; Inese Mierina; Anatoly Mishnev; Mara Jure
Journal:  Acta Crystallogr E Crystallogr Commun       Date:  2018-05-15
  1 in total

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