OBJECTIVES: To determine the relative frequency of prostate cancer among surgical specimens, and among prostate specimens received at the pathology department ,University Hospital Calabar. METHODS: Histology records were reviewed for the following: total number of histology specimens received; total number of prostate specimens; total number of prostate cancer; and the total number of cancers in males during the study period. Histology sections 4-5microns thick were cut from paraffin blocks and stained by Haematoxylin and Eosin (H&E). Histopathologic specimens were classified using the grading system of tumour differentiation described by Gleason and associates. RESULTS: One hundred and twenty three cancers of the prostate were received, constituting 2% of the total surgical specimens and 31% of prostate specimens. Thirty three cases (27%) could not be analyzed; therefore the study is based on 90 prostate cancer specimens. Eighty nine (99%) cases were epithelial tumours (adenocarcinoma.) There was a single mesenchymal tumour (rhabdomyosarcoma) (1%). The commonest grade in this study was the high grade (Gleason grade IV). CONCLUSIONS: We observed that prostate cancer is a common among males (all sites) diagnosed at the University Hospital Calabar, with a peak incidence between the ages of 61 - 70 years (seventh decade).
OBJECTIVES: To determine the relative frequency of prostate cancer among surgical specimens, and among prostate specimens received at the pathology department ,University Hospital Calabar. METHODS: Histology records were reviewed for the following: total number of histology specimens received; total number of prostate specimens; total number of prostate cancer; and the total number of cancers in males during the study period. Histology sections 4-5microns thick were cut from paraffin blocks and stained by Haematoxylin and Eosin (H&E). Histopathologic specimens were classified using the grading system of tumour differentiation described by Gleason and associates. RESULTS: One hundred and twenty three cancers of the prostate were received, constituting 2% of the total surgical specimens and 31% of prostate specimens. Thirty three cases (27%) could not be analyzed; therefore the study is based on 90 prostate cancer specimens. Eighty nine (99%) cases were epithelial tumours (adenocarcinoma.) There was a single mesenchymal tumour (rhabdomyosarcoma) (1%). The commonest grade in this study was the high grade (Gleason grade IV). CONCLUSIONS: We observed that prostate cancer is a common among males (all sites) diagnosed at the University Hospital Calabar, with a peak incidence between the ages of 61 - 70 years (seventh decade).
Entities:
Keywords:
analysis; cancer; grade; histologic; pattern; prostate; role
Authors: M A Jackson; B S Ahluwalia; J Herson; M Y Heshmat; A G Jackson; G W Jones; S K Kapoor; J Kennedy; J Kovi; A O Lucas; E O Nkposong; E Olisa; A O Williams Journal: Cancer Treat Rep Date: 1977 Mar-Apr
Authors: Robert P Caruso; Benjamin Levinson; Jonathan Melamed; Rosemary Wieczorek; Samir Taneja; David Polsky; Caroline Chang; Anne Zeleniuch-Jacquotte; Konstantin Salnikow; Herman Yee; Max Costa; Iman Osman Journal: Clin Cancer Res Date: 2004-01-01 Impact factor: 12.531